In vitro evaluation of microparticles with Laurus nobilis L. extract prepared by spray-drying for application in food and pharmaceutical products

摘要

Laurus nobilis L. is an aromatic evergreen tree, rich in phenolic compounds that grant it therapeutic properties (e.g. antioxidant, anti-inflammatory and antiviral). However, polyphenols are very sensitive to external conditions, being necessary to develop an adequate delivery system to protect these active ingredients, reducing their reactivity with external factors, and allowing their release at the right place and time. In this context, in this experimental work, the design of microparticles containing L. nobilis L. extract was studied, using the spray-drying as encapsulation technique and the modified chitosan, sodium alginate and arabic gum as encapsulating agents. At the end, the L. nobilis L. extract microparticles were characterized, and their effectiveness evaluated. The microparticles containing the L. nob ilis L. extract were obtained with product yields that ranged from 48.0% to 53.7%, and encapsulation efficiencies between 72.9% and 99.3%.