Inflammatory Response to Anesthesia and Ways to Attenuate It

摘要

Inflammation is a response of the body to tissue injury. It is a rapid and highly controlled humoral and cellular response. Surgery, burns, major trauma, and sepsis are all associated with major inflammatory responses. Inflammation is essential for tissue reconstitu-tion, but an overactive inflammatory response may destroy rather than protect and may lead to multiple perioperative and postoperative complications, for example, systemic inflammatory response syndrome (SIRS), wound healing disturbances, postoperative infections, and postoperative pain leading to sepsis, multiple organ dysfunction (MOD), and death.