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Molecular classification of Crohn's disease reveals two clinically relevant subtypes

机译:克罗恩病的分子分类揭示了两个临床相关的亚型

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摘要

Objective The clinical presentation and course of Crohn's disease (CD) is highly variable. We sought to better understand the cellular and molecular mechanisms that guide this heterogeneity, and characterise the cellular processes associated with disease phenotypes.
机译:目的是克罗恩疾病(CD)的临床介绍和过程是高度变化的。 我们寻求更好地理解引导这种异质性的细胞和分子机制,并表征与疾病表型相关的细胞过程。

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    Univ North Carolina Chapel Hill Dept Genet 7340B Med Biomol Res Bldg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Genet 7340B Med Biomol Res Bldg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Curriculum Bioinformat &

    Computat Biol Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Genet 7340B Med Biomol Res Bldg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Ctr Gastrointestinal Biol &

    Dis Chapel Hill NC 27517 USA;

    Cedars Sinai Med Ctr F Widjaja Fdn Inflammatory Bowel &

    Immunobiol Res Los Angeles CA 90048 USA;

    Univ North Carolina Chapel Hill Dept Surg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Surg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Surg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Genet 7340B Med Biomol Res Bldg Chapel Hill NC 27517 USA;

    Univ North Carolina Chapel Hill Dept Genet 7340B Med Biomol Res Bldg Chapel Hill NC 27517 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 消化系及腹部疾病;
  • 关键词

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