BCL-2 system analysis identifies high-risk colorectal cancer patients

Lindner Andreas U.; Salvucci Manuela; Morgan Clare; Monsefi Naser; Resler Alexa J.; Cremona Mattia; Curry Sarah; Toomey Sinead; OByrne Robert; Bacon Orna; Stuhler Michael; Flanagan Lorna; Wilson Richard; Johnston Patrick G.; Salto-Tellez Manuel; Camilleri-Broet Sophie; McNamara Deborah A.; Kay Elaine W.; Hennessy Bryan T.; Laurent-Puig Pierre; Van Schaeybroeck Sandra; Prehn Jochen H. M.

首页> 外文期刊>Gut: Journal of the British Society of Gastroenterology >BCL-2 system analysis identifies high-risk colorectal cancer patients

【24h】

BCL-2 system analysis identifies high-risk colorectal cancer patients

机译：BCL-2系统分析识别高风险结直肠癌患者

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Objective The mitochondrial apoptosis pathway is controlled by an interaction of multiple BCL-2 family proteins, and plays a key role in tumour progression and therapy responses. We assessed the prognostic potential of an experimentally validated, mathematical model of BCL-2 protein interactions (DR_MOMP) in patients with stage III colorectal cancer (CRC).

机译：目的通过多个Bcl-2家族蛋白的相互作用来控制线粒体细胞凋亡途径，并在肿瘤进展和治疗反应中起关键作用。我们评估了III阶段结直肠癌（CRC）患者的实验验证的BCL-2蛋白相互作用（DR_MOMP）的实验验证数学模型的预后潜力。

著录项

来源
《Gut: Journal of the British Society of Gastroenterology》 |2017年第12期|共8页
作者
Lindner Andreas U.; Salvucci Manuela; Morgan Clare; Monsefi Naser; Resler Alexa J.; Cremona Mattia; Curry Sarah; Toomey Sinead; OByrne Robert; Bacon Orna; Stuhler Michael; Flanagan Lorna; Wilson Richard; Johnston Patrick G.; Salto-Tellez Manuel; Camilleri-Broet Sophie; McNamara Deborah A.; Kay Elaine W.; Hennessy Bryan T.; Laurent-Puig Pierre; Van Schaeybroeck Sandra; Prehn Jochen H. M.;
展开▼
作者单位

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Dept Mol Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Dept Physiol &

Med Phys 123 St Stephens Green Dublin 2 Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Queens Univ Belfast Sch Med Ctr Canc Res &

Cell Biol Belfast Antrim North Ireland;

Queens Univ Belfast Sch Med Ctr Canc Res &

Cell Biol Belfast Antrim North Ireland;

Queens Univ Belfast Sch Med Ctr Canc Res &

Cell Biol Belfast Antrim North Ireland;

Univ Paris 05 Dept Pathol UMR S 1147 Paris France;

Royal Coll Surgeons Ireland Dept Surg Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

Univ Paris 05 UMR S 1147 Paris France;

Queens Univ Belfast Sch Med Ctr Canc Res &

Cell Biol Belfast Antrim North Ireland;

Royal Coll Surgeons Ireland Ctr Syst Med Dublin Ireland;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词

相似文献

外文文献
中文文献
专利

1. BCL-2 system analysis identifies high-risk colorectal cancer patients [J] . Lindner Andreas U., Salvucci Manuela, Morgan Clare, Gut: Journal of the British Society of Gastroenterology . 2017,第12期

机译：BCL-2系统分析识别高风险结直肠癌患者
2. A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer [J] . Yuji Toiyama, Yoshinaga Okugawa, Koji Tanaka, Gastroenterology . 2017,第6期

机译：用于鉴定溃疡性结肠炎相关结直肠癌的高风险患者的甲基化MicroRNA生物标志物。
3. hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy [J] . Leonardo Muratori OncoTargets and therapy . 2016,第2期

机译：hERG1阳性和Glut-1阴性可识别高危TNM I和II期大肠癌患者，无论辅助化疗如何
4. Identifying High-Risk Breast Cancer Patients Using Microarray and Clinical Data [C] . Azni Nasuha Ngisa, Ong Huey Fang IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：使用微阵列和临床数据鉴定高危乳腺癌患者
5. Identifying Potential Therapeutic Compounds for Patient Specific Models of Colorectal Cancer Using Drosophila [D] . Arroyo, Daniel. 2020

机译：使用果蝇鉴定患者特异性癌症患者特异性模型的潜在治疗化合物
6. Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models [O] . Alice C. O’Farrell, Monika A. Jarzabek, Andreas U. Lindner, 2020

机译：实施系统建模和分子成像以预测直肠癌患者衍生异种移植模型BCL-2抑制的疗效
7. Nomogram model characterized by mutant genes and clinical indexes to identify high-risk patients with stage III/IV colorectal cancer [O] . Kai Liu, Cui Wang, Jiefu Wang, 2020

机译：纯粹基因的载体模型，突变基因和临床指标，以鉴定III阶段/ IV型结直肠癌的高危患者

BCL-2 system analysis identifies high-risk colorectal cancer patients

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅