Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice

Dogru Murat; Shinzawa Megumi; Kojima Takashi; Shimizu Takahiko; Tsubota Kazuo

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Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice

机译：CU，Zn-超氧化物歧化酶-1（SOD1）的年龄相关结膜P2Y2受体改变 - Knockout Dring Eye模型小鼠

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Purpose: To investigate the effects of aging on the conjunctival P2Y2 receptors, tear functions, and corneal epithelial status from 10 to 50 weeks in the Sod1(-/-) in comparison with the wild-type mice.

机译：目的：研究与野生型小鼠相比，在SOD1（ - / - ）中探讨老化对结膜P2Y2受体，撕裂功能和角膜上皮状态的影响。

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来源
《Eye & contact lens 》 |2019年第6期| 共5页
作者
Dogru Murat; Shinzawa Megumi; Kojima Takashi; Shimizu Takahiko; Tsubota Kazuo;
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作者单位

Keio Univ Sch Med Dept Ophthalmol Shinjuku Ku Shinanomachi 35 Tokyo 1608582 Japan;

Keio Univ Sch Med Dept Ophthalmol Shinjuku Ku Shinanomachi 35 Tokyo 1608582 Japan;

Keio Univ Sch Med Dept Ophthalmol Shinjuku Ku Shinanomachi 35 Tokyo 1608582 Japan;

Chiba Univ Grad Sch Med Dept Adv Aging Med Chuo Ku Chiba Japan;

Keio Univ Sch Med Dept Ophthalmol Shinjuku Ku Shinanomachi 35 Tokyo 1608582 Japan;

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原文格式 PDF
正文语种 eng
中图分类眼科学 ;
关键词
Dry eye; Aging; Conjunctiva; P2Y2 receptor;

机译：干眼;老化;结膜;p2y2受体;

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专利

1. Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice [J] . Dogru Murat, Shinzawa Megumi, Kojima Takashi, Eye & contact lens . 2019 ,第6期

机译：CU，Zn-超氧化物歧化酶-1（SOD1）的年龄相关结膜P2Y2受体改变 - Knockout Dring Eye模型小鼠
2. Age-related dysfunction of the lacrimal gland and oxidative stress: Evidence from the Cu,Zn-superoxide dismutase-1 (Sod1) knockout mice [J] . KojimaT., WakamatsuT.H., DogruM., American Journal of Pathology: Official Publication of the American Association of Pathologists . 2012 ,第5期

机译：年龄相关的泪腺功能障碍和氧化应激：铜锌超氧化物歧化酶-1（Sod1）基因敲除小鼠的证据。
3. Age-Related Dysfunction of the Lacrimal Gland and Oxidative StressEvidence from the Cu,Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice [J] . Takashi Kojima, Tais H. Wakamatsu, Murat Dogru, The American journal of pathology. . 2012 ,第5期

机译：年龄相关的泪腺功能障碍和氧化应激从铜，锌超氧化物歧化酶-1（Sod1）基因敲除小鼠的证据。
4. Serotonin 1B receptor knockout mice as an animal model of vulnerability to drugs of abuse [D] . Scearce-Levie, Kimberly Ann 2002

机译：血清素1B受体敲除小鼠是易受滥用药物影响的动物模型
5. The Effects of 3 Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications [O] . Yukari Yagi-Yaguchi, Takashi Kojima, Kazunari Higa, 2020

机译：3％Diquafosol钠滴眼液对抗青光眼眼药治疗的小鼠泪液功能和CuZn-超氧化物歧化酶-1（Sod1）敲除小鼠的眼表的影响
6. The Effects of 3 Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications [O] . Yukari Yagi-Yaguchi, Takashi Kojima, Kazunari Higa, 2020

机译：用抗原瘤眼药药物治疗3％Diquafosol钠滴眼液对Cu，Zn-超氧化物歧化酶-1（SOD1）敲除小鼠的撕裂功能和眼表面的影响
7. Reduced Acetylcholine Receptor Density, Morphological Remodeling, and Butyrylcholinesterase Activity Can Sustain Muscle Function in Acetylcholinesterase Knockout Mice [R] . Adler, M. , Manley, H. A. , Deshpande, S. S. , 2004

机译：降低乙酰胆碱受体密度，形态重塑和丁酰胆碱酯酶活性可维持乙酰胆碱酯酶基因敲除小鼠的肌肉功能

Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice

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