Genetic variation underlies epigenomic variation and the consequences of DNMT3A mutation in hematopoietic stem cells

Jennifer Trowbridge; Rebecca Bell; Catrina Spruce; Anna Tyler; Robyn Ball; Vivek Philip; Dan Gatti; Narayanan Raghupathy; Romy Kurasawe; Kira Young; Mary Ann Handel; Michael Stitzel; Gary Churchill; Kenneth Paigen; Petko Petkov; Gregory Carter

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Genetic variation underlies epigenomic variation and the consequences of DNMT3A mutation in hematopoietic stem cells

机译：遗传变异是表观胸肉变异及DNMT3A突变在造血干细胞中的影响

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来源
《Experimental Hematology: Official Publication of the International Society for Experimental Hematology 》 |2017年第2017期| 共1页
作者
Jennifer Trowbridge; Rebecca Bell; Catrina Spruce; Anna Tyler; Robyn Ball; Vivek Philip; Dan Gatti; Narayanan Raghupathy; Romy Kurasawe; Kira Young; Mary Ann Handel; Michael Stitzel; Gary Churchill; Kenneth Paigen; Petko Petkov; Gregory Carter;
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作者单位

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory for Genomic Medicine;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory for Genomic Medicine;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

The Jackson Laboratory;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病 ;
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专利

1. Genetic variation underlies epigenomic variation and the consequences of DNMT3A mutation in hematopoietic stem cells [J] . Jennifer Trowbridge, Rebecca Bell, Catrina Spruce, Experimental Hematology: Official Publication of the International Society for Experimental Hematology . 2017 ,第期

机译：遗传变异是表观胸肉变异及DNMT3A突变在造血干细胞中的影响
2. Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non-myeloablative conditioning hematopoietic stem cell transplantation [J] . Schmalbrock Laura K., Bonifacio Lynn, Bill Marius, Bone marrow transplantation . 2018 ,第5期

机译：DNMT3A R882突变在非霉菌调理造血干细胞移植中的AML患者中的预后相关性
3. The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels [J] . Erik Axelsson, Ingrid Ljungvall, Priyasma Bhoumik, PLoS Genetics . 2021 ,第9期

机译：探测遗传变异的养殖形成积累的遗传后果及骑士王克斯·斯潘尼尔王莹，王莹，王莹，王莹
4. Analysis of Cancer Somatic Mutations Taking into Consideration Human Genetic Variations [C] . Bin He, Hanaa Torkey, Azam S. Z. Moosavi, International Conference on Bioinformatics and Computational Biology . 2014

机译：考虑人类遗传变异的癌症体突变分析
5. Cell-to-cell genetic variation in the mammalian central nervous system. [D] . Kaushal, Dhruv. 2003

机译：哺乳动物中枢神经系统中的细胞间遗传变异。
6. Non-mutational (epigenomic) structural variation in the transcriptome of cancer cells [O] . E. Aubrey Thompson 2015

机译：癌细胞转录组中的非突变（表基因组）结构变异
7. Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations [O] . Xu, Yang, Sun, Yanjun, Shen, Hongjie, 2015

机译：同种异体造血干细胞移植可提高DNmT3a突变的细胞遗传学正常成人急性髓细胞白血病患者的生存率

Genetic variation underlies epigenomic variation and the consequences of DNMT3A mutation in hematopoietic stem cells

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