Adjuvant effect of Bacillus firmus on the expression of cytokines and toll-like receptors in mouse nasopharynx-associated lymphoid tissue (NALT) after intranasal immunization with inactivated influenza virus type A

摘要

Due to the persisting threat of development of new highly pathogenic influenza A subtypes a mucosal vaccination which would induce a potent and cross-protective reaction is desirable We succeeded in mucosal immunization of mice with an inactivated influenza A virus by using delipidated Bacillus firm us (DBF) as adjuvant