Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy

Beebe A.; Mahne A.; Mauze S.; Joyce-Shaikh B.; Cua D.; Jain R.

首页> 外文期刊>European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) >Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy

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Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy

机译：肿瘤免疫疗法靶向T细胞耗尽和共刺激信号的调节性T细胞耗尽和共刺激信号的双重作用

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《European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)》 |2016年第null期|共1页
作者
Beebe A.; Mahne A.; Mauze S.; Joyce-Shaikh B.; Cua D.; Jain R.;
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Merck &

Co Inc Discovery Res Palo Alto CA USA;

Merck &

Co Inc Discovery Res Palo Alto CA USA;

Merck &

Co Inc Discovery Res Palo Alto CA USA;

Merck &

Co Inc Discovery Res Palo Alto CA USA;

Merck &

Co Inc Discovery Res Palo Alto CA USA;

Merck &

Co Inc Discovery Res Palo Alto CA USA;

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正文语种 eng
中图分类肿瘤学;
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1. Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy [J] . Beebe A., Mahne A., Mauze S., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：调节性T细胞耗竭和共刺激信号在激动性GITR靶向肿瘤免疫治疗中的双重作用
2. Authentic GITR Signaling Fails To Induce Tumor Regression unless Foxp(3+) Regulatory T Cells Are Depleted [J] . Kim Young H., Shin Su M., Choi Beom K., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2015,第10期

机译：除非Foxp（3+）调节性T细胞被耗竭，否则真实的GITR信号无法诱导肿瘤消退
3. Authentic GITR Signaling Fails To Induce Tumor Regression unless Foxp3+ Regulatory T Cells Are Depleted [J] . Young H. Kim, Su M. Shin, Beom K. Choi, The journal of immunology . 2015,第10期

机译：除非Foxp3 +调节性T细胞耗尽，否则真实的GITR信号无法诱导肿瘤消退
4. Hitting the Gas: Quantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Co-Stimulatory Immune Checkpoint Receptors [C] . Caron Winslow, Jun Wang, Michael Beck, Protein Engineering Summit. . 2018

机译：击中气体：定量细胞的生物测定，以推进靶向共刺激免疫检查点受体的免疫疗程
5. Augmentation of natural killer cell-mediated anti-tumor effects by molecular targeting and regulatory T cell depletion. [D] . Hallett, William H. D. 2008

机译：通过分子靶向和调节性T细胞耗竭增强自然杀伤细胞介导的抗肿瘤作用。
6. Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells [O] . Kuibeom Ko, Sayuri Yamazaki, Kyoko Nakamura, 2012

机译：激动性抗GITR mAb治疗晚期肿瘤及其对肿瘤浸润性Foxp3 + CD25 + CD4 +调节性T细胞的影响
7. Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy [O] . Ashley E. Mahne, Smita Mauze, Barbara Joyce-Shaikh, 2016

机译：用于肿瘤免疫疗法的激动性GITR靶向治疗T细胞耗尽和共刺激信号的双重作用

Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy

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