P-162: Comprehensive geriatric and frailty assessment in a sample of older patients with severe aortic stenosis considered as candidates for transcatheter aortic valve implantation

摘要

Background: Frailty is present in patients screened for transcatheter aortic valve implantation (TAVI). The aim of this study was to describe the characteristics of older people with severe aortic stenosis (SAS) underwent TAVI. Methods: A prospective study of patients with SAS in a Cardio-Geriatric consult was carried out. Socio-demographic, clinical, functional status [Barthel index (BI) Functional Ambulation Category (FAC)], cognitive status [Short Portable Mental Status Questionnaire (SPMSQ)], analytical and nutritional variables [body mass index (BMI)] were registered. Frailty was considered when Short Physical Performance Battery (SPPB)<9, gait speed<8 m/s or hand grip strength<13 kg in women or<23 kg in men. Results: One hundred and thirty one patients were included. Mean age was 82.03 ± 6.73 years, 55% female. One hundred and two patients underwent TAVI. Mean values were: BI: 94.65 ± 6.73, FAC: 4.68 ± 0.69, SPMSQ: 0.97 ± 1.34, gait speed 0.72 m/ s ± 0.25, hand grip strength: 17.3 ± 6.33 kg in women and 29.47 ± 7.61 kg in men, SPPB: 8.83 ± 2.87, serum creatinine 1.14 ± 0.52 mg/dl. Comorbidities registered were diabetes: 34.9%, chronic obstructive pulmonary disease: 17.3%, cancer: 15.7%, chronic renal failure: 13.3%. Prevalence of frailty was 63.7%, 37.3%, 25.9%, 13.3% according to gait speed, SPPB, and handgrip strength (women and men) criteria respectively. Conclusion: Patients with SAS underwent TAVI were in a good functional and mental status, although frailty was very frequently detected. Frailty must be more extensively studied in these patients in order to know their predictive power for bad outcomes.