Rapid improvement of muscle weakness post‐thymectomy indicates good long‐term neurological outcome in patients with ocular myasthenia gravis

摘要

Background and purpose This study was conducted to evaluate whether post‐thymectomy rapid remission of ocular myasthenia gravis ( oMG ) is a prognostic indicator of good long‐term neurological outcome. Methods Eighty‐four oMG patients who underwent thymectomy at our institute were enrolled. The incidence of 5‐year complete stable remission ( CSR ) was compared between patients with rapid remission of MG status (1?month after surgery) and those with non‐rapid remission. Results Kaplan–Meier survival analysis indicated that the incidence of CSR was higher in oMG patients with rapid remission than in those without rapid remission ( P? ? 0.001). Multivariate analysis showed that rapid remission (odds ratio 16.34, 95% confidence interval 3.58–74.60, P? ? 0.001) is an independent prognostic factor for CSR . Conclusion Postoperative rapid remission of MG status predicts a higher likelihood of complete remission in patients with oMG .