Impaired left ventricular mechanics and functional reserve are associated with reduced exercise capacity in patients with hypertrophic cardiomyopathy

Wu Xiao-Peng; Li Yi-Dan; Zhang Miao; Zhu Wei-Wei; Cai Qi-Zhe; Jiang Wei; Sun Lan-Lan; Ding Xue-Yan; Ye Xiao-Guang; Qin Yun-Yun; Lu Xiu-Zhang

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Impaired left ventricular mechanics and functional reserve are associated with reduced exercise capacity in patients with hypertrophic cardiomyopathy

机译：受损的左心室力学和功能储备与肥厚性心肌病患者的运动能力降低有关

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Background: Reduced metabolic equivalents (METs) are an indicator of exercise intolerance, which predicts poor prognosis in hypertrophic cardiomyopathy (HCM) patients. We sought to evaluate the changes in left ventricular (LV) mechanics and functional reserves, as well as their association with functional capacity in HCM patients.

机译：背景：降低的代谢等同物（METS）是运动不耐受的指标，其预测肥厚性心肌病（HCM）患者的预后差。我们试图评估左心室（LV）力学和功能储备的变化，以及HCM患者中功能能力的关系。

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来源
《Echocardiography.》 |2019年第2期|共10页
作者
Wu Xiao-Peng; Li Yi-Dan; Zhang Miao; Zhu Wei-Wei; Cai Qi-Zhe; Jiang Wei; Sun Lan-Lan; Ding Xue-Yan; Ye Xiao-Guang; Qin Yun-Yun; Lu Xiu-Zhang;
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作者单位

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

Capital Med Univ Beijing Chao Yang Hosp Ctr Heart Dept Echocardiog Beijing Peoples R China;

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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
exercise stress echocardiography; functional reserve; hypertrophic cardiomyopathy; speckle tracking imaging;

机译：运动应激超声心动图;功能储备;肥厚性心肌病;斑点跟踪成像;

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专利

1. Impaired left ventricular mechanics and functional reserve are associated with reduced exercise capacity in patients with hypertrophic cardiomyopathy [J] . Wu Xiao-Peng, Li Yi-Dan, Zhang Miao, Echocardiography. . 2019,第2期

机译：受损的左心室力学和功能储备与肥厚性心肌病患者的运动能力降低有关
2. Extent of late gadolinium enhancement on cardiovascular magnetic resonance imaging and its relation to left ventricular longitudinal functional reserve during exercise in patients with hypertrophic cardiomyopathy [J] . MoonJ., HongY.J., KimY.-J., Circulation journal . 2013,第7期

机译：肥厚型心肌病患者运动中晚期g增强在心血管磁共振成像中的作用及其与左室纵向功能储备的关系
3. Extent of Late Gadolinium Enhancement on Cardiovascular Magnetic Resonance Imaging and Its Relation to Left Ventricular Longitudinal Functional Reserve During Exercise in Patients With Hypertrophic Cardiomyopathy [J] . Jeonggeun Moon, Yoo Jin Hong, Young-Jin Kim, Circulation journal . 2013,第7期

机译：肥厚型心肌病患者运动过程中晚期Ga增强程度对心血管磁共振成像的影响及其与左心室纵向功能储备的关系
4. Does a Maximum Left Ventricular Thickness Greater than 30 mm Identify Patients with Hypertrophic Cardiomyopathy at Risk of Sudden Death? [C] . I. OLIVOTTO, F. CECCHI International Workshop on Cardiac Arrhythmias . 2004

机译：最大左心室厚度大于30毫米，判断患有猝死风险的肥厚性心肌病的患者吗？
5. Exercise prescription in patients with left ventricular dysfunction: A comparison of conventional methods of exercise prescription with a method utilizing respiratory measures and a Doppler assessment of left ventricular function. [D] . Normandin, Edgar Albert. 1989

机译：左心功能不全患者的运动处方：传统运动处方方法与利用呼吸测量和多普勒评估左心功能的方法的比较。
6. Impaired Right Ventricular Mechanics at Rest and During Exercise Are Associated With Exercise Capacity in Patients With Hypertrophic Cardiomyopathy [O] . Xiao‐Peng Wu, Yi‐Dan Li, Yi‐Dan Wang, 2019

机译：肥厚型心肌病患者休息和运动期间右心室力学的受损与运动能力相关
7. P235Relation between myocardial deformation by three-dimensional speckle tracking analysis , control of the hypertension and functional capacity in patients with systemic hypertensionP236Obstructive sleep apnoea is often under-recognised in patients with acute myocardial infarction, but commonly contributes to left ventricular diastolic dysfunctionP237Intrinsic left ventricular dysfunction in Behcet disease in comparison with systemic disease activity: insights from speckle tracking echocardiographyP238Echocardiography changes during singleton and twin pregnancyP239Proposal of two new echocardiographic parameters for the differentiation of pre-capillary from post-capillary pulmonary hypertensionP240The coincidence of implanted device and number of electrodes with the presence of residual fibrotic tissue after transvenous leads extraction assessed in echocardiographic examP241Hemoglobin is an independent predictor of left ventricular hypertrophy in postmenopausal women but not in premenopausal womenP242Left ventricular longitudinal deformation impairment in patients with psoriasis is linked with immunologic activationP243Impaired diastolic functions and left atrial mechanical functions in patients with vitamin-D deficiencyP244Modification of cardiac and vascular function secondary to insulin resistanceP245Impaired right ventricular function is not related to serum galectin-3 concentration in patients with repaired tetralogy of fallotP246Age-adjusted indices of right ventricular (RV) longitudinal function do not adequately reflect the global RV contraction in children with repaired congenital heart defects and RV volume overloadP247Relationship between fractional flow reserve and dobutamine stress echocardiography in coronary artery diseaseP248A retrospective observational comparative study on the negative predictive value of nuclear testing vs. stress echo in pre-operative assessment for patients undergoing solid organ transplantionP249The detection of viable myocardium by dobutamine stress speckle tracking echocardiography in patients with coronary artery diseaseP250VO2 flattening during exercise in heart failure: evidence for a combined low cardiac output and inefficient O2 extractionP251 The dynamic assessment of alveolar-capillary barrier during exercise-echocardiography in heart failure patients with reduced ejection fractionP252The effect of exercise training on cardiac function during exercise stress echo in patients with type 2 diabetes and diastolic dysfunctionP253Age-related maximal exercise O2 extraction differences in a population of apparently healthy subjects at cardiovascular riskP254Difference in the changes of functional mitral regurgitation between semisupine ergometer and handgrip exerciseP255Correlation of annulus size assessed by echo 2d, 3d and multidetector computed tomography in patients undergoing transcatheter aortic valve implantationP256Mitral annulus dynamics: from normal to extensive mixomatous disease-a three-dimensional transoesophageal studyP257Left atrial appendage closure: an echo point of view of 55 casesP258Effect of catheter-based renal denervation on left ventricular function, mass and (un)twist with two-dimensional speckle tracking echocardiographyP259Associations of microRNAs gene expression in peripheral blood mononuclear cells and left ventricular global longitudinal peak strain in patients with essential hypertension [O] . I. Craciunescu, N. Ngiam, BJ. Sun, 2016

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Impaired left ventricular mechanics and functional reserve are associated with reduced exercise capacity in patients with hypertrophic cardiomyopathy

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