Age-Related Changes in Tissue Value Properties in Children Simultaneous Quantification of Relaxation Times and Proton Density Using Synthetic Magnetic Resonance Imaging

摘要

Objectives: The properties of brain tissue undergo dynamic changes during maturation. T1 relaxation time (T1), T2 relaxation time (T2), and proton density (PD) are now simultaneously quantifiable within a clinically acceptable time, using a synthetic magnetic resonance imaging (MRI) sequence. This study aimed to provide age-specific reference values for T1, T2, and PD in children, using synthetic MRI.