Association between maternal vascular murmur and the small‐for‐gestational‐age fetus with abnormal umbilical artery Doppler flow

Riknagel Diana; Farlie Richard; Hedegaard Morten; Humaidan Peter; Struijk Johannes J.

摘要

Abstract <section numbered="no" xml:id="ijgo12268-sec-0001"> <title type="main">Objective > To investigate the association between maternal vascular murmurs ( <fc>MVM</fc> s) and fetal growth restriction (defined as small‐for‐gestational‐age [ <fc>SGA</fc> ] fetus) and abnormal Doppler pulsatility index ( <fc>PI</fc> ) of the uterine and/or umbilical arteries. </section> <section numbered="no" xml:id="ijgo12268-sec-0002"> <title type="main">Methods > A cross‐sectional study of women aged 18?years or older with a singleton pregnancy at 28–34?weeks was conducted at Regional Hospital Viborg, Denmark, between May 1 and August 1, 2013. Ultrasound fetal biometry was performed and the Doppler <fc>PI</fc> of the umbilical and uterine arteries was determined. An estimated fetal weight ( <fc>EFW</fc> ) at or below the 10th percentile was defined as <fc>SGA</fc> . Microphone recordings from the lower abdomen were divided into heart valve sounds and <fc>MVM</fc> s. </section> <section numbered="no" xml:id="ijgo12268-sec-0003"> <title type="main">Results > The final analysis included 63 participants, with 25 classified as <fc>SGA</fc> and 38 as non‐ <fc>SGA</fc> . The mean pregnancy duration was 32.4?±?1.4?weeks. In total, 17 participants had <fc>MVM</fc> s. There was a clear association between <fc>MVM</fc> s and a composite of <fc>SGA</fc> and an abnormal <fc>PI</fc> of the uterine and/or the umbilical artery ( P 0.001), but not between <fc>MVM</fc> s and <fc>SGA</fc> only ( P= 0.154). </section> <section numbered="no" xml:id="ijgo12268-sec-0004"> <title type="main">Conclusion > Maternal vascular murmurs are significantly associated with fetal growth restriction, but not with <fc>SGA</fc> per se. </section> </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml：id =“ijgo12268-abs-abs-0001”> <标题类型=“main”>抽象</ title> < numbyed =“否”xml：id =“ijgo12268-sec-0001”> <标题类型=“main”>目标</ title> >调查母体血管杂音之间的关联（<fc> mvm </ fc之间的关联> s）和胎儿生长限制（定义为子宫和/或胎儿的小于胎儿年龄[<FC> SGA </ FC>]胎儿）和异常多普勒脉动性指数（<FC> PI </ FC>）脐动脉。 </ p> </ section> <secto numbyed =“no”xml：id =“ijgo12268-sec-0002”> <标题类型=“main”>方法</ title> >女性的横截面研究年龄18岁？岁月或以上的单身怀孕28-34岁？周是在2013年5月1日至8月1日至8月1日至8月1日之间的丹麦地区医院Viborg进行的。进行了超声胎儿生物学和多普勒<Fc> Pi </ Fc>确定了脐带和子宫动脉。在第10百分位或低于10百分位的估计胎儿重量（<Fc> EFW </ Fc>）被定义为<Fc> SGA </ Fc>。从下腹部的麦克风录音分为心脏阀声音和<FC> MVM> S. </ p> </ section> <部分编号=“否”xml：id =“ijgo12268-sec-0003”> <标题类型=“main”>结果</ title> >最终分析包括63名参与者， 25分为<FC> SGA </ FC>和38作为非<FC> SGA </ FC>。平均妊娠持续时间为32.4？±1.4？周。总共有17名参与者<FC> MVM </ FC> S. <Fc> MVM </ FC> S和子宫和/或脐动脉的异常<FC> Pi </ Fc>之间存在明显的关联和<FC> SGA </ FC>的复合物（<FC> Pi </ Fc>（<i > P＆ </ i> 0.001），但不在<Fc> MVM> S和<FC> SGA </ Fc>之间（ P = </ I> 0.154）。 </ p> </段> <部分编号=“否”XML：ID =“IJGO12268-SEC-0004”> <标题类型=“main”>结论</标题> >母体血管杂音与母体血管杂音显着相关胎儿生长限制，但不是<FC> SGA </ FC>本身。 </ p> </ section> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" > 著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-21245/'>《International journal of gynecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 》</a> <b style="margin: 0 2px;">|</b><span>2017年第2期</span><b style="margin: 0 2px;">|</b> <span>共6页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Riknagel Diana&option=202" target="_blank" rel="nofollow">Riknagel Diana;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Farlie Richard&option=202" target="_blank" rel="nofollow">Farlie Richard;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hedegaard Morten&option=202" target="_blank" rel="nofollow">Hedegaard Morten;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Humaidan Peter&option=202" target="_blank" rel="nofollow">Humaidan Peter;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Struijk Johannes J.&option=202" target="_blank" rel="nofollow">Struijk Johannes J.;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Health Science and TechnologyAalborg UniversityAalborg Denmark;</p> <p>Herning HospitalHerning Denmark;</p> <p>Juliane Marie CentreRigshospitaletCopenhagen Denmark;</p> <p>Faculty of HealthAarhus UniversityAarhus Denmark;</p> <p>Department of Health Science and TechnologyAalborg UniversityAalborg Denmark;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li> <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span> <a href="https://www.zhangqiaokeyan.com/clc/197.html" title="妇产科学">妇产科学 ;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Arterial sound analysis&option=203" rel="nofollow">Arterial sound analysis;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Intrauterine growth restriction&option=203" rel="nofollow">Intrauterine growth restriction;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Maternal vascular murmur&option=203" rel="nofollow">Maternal vascular murmur;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Prenatal monitoring&option=203" rel="nofollow">Prenatal monitoring;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Umbilical artery flow&option=203" rel="nofollow">Umbilical artery flow;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Uterine artery flow&option=203" rel="nofollow">Uterine artery flow;</a> </p> <div class="translation"> 机译：动脉声音分析;宫内生长限制;产妇血管杂音;产前监测;脐动脉流动;子宫动脉流动; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704023018425.html">Association between maternal vascular murmur and the small‐for‐gestational‐age 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href="/academic-degree-domestic_mphd_thesis/020311934292.html">彩色多普勒超声联合检测胎儿大脑中动脉与脐动脉、肾动脉阻力指标比值预测妊高征胎儿宫内缺氧</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈禹&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 陈禹</a> <span> . 2012</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061202965168.html">使用来自母体血液的胎儿细胞捕获的胎儿诊断学</a> <b>[P]</b> . <span> 中国专利： CN105324666B </span> <span> . 2018.07.27</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120109712617.html">一种基于母体的胎儿外膜滋养层细胞的胎儿遗传检测方法</a> <b>[P]</b> . <span> 中国专利： CN107236809A </span> <span> . 2017-10-10</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130433154539.html">Prevention of damage in hippocampus of fetus/newborn infant due to maternal gestational hypertension</a> <b>[P]</b> . <span> 外国专利：  US2008038288A1 </span> <span> . 2008-02-14</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：预防母体妊娠高血压对胎儿/新生儿海马的损害 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130432073558.html">Prevention of damage in hippocampus of fetus/newborn infant due to maternal gestational hypertension</a> <b>[P]</b> . <span> 外国专利：  EP1920776A1 </span> <span> . 2008-05-14</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：预防母体妊娠高血压对胎儿/新生儿海马的损害 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130425314426.html">METHOD FOR DIAGNOSING LOW MASS OF FETUS THAT DOES NOT MATCH GESTATIONAL AGE IN MULTIPLE GESTATION</a> <b>[P]</b> . <span> 外国专利：  UA62149U </span> <span> . 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