Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient KitW-sh/W-sh mice

ShoheiShibagaki; SatokoTahara-Hanaoka; TakashiHiroyama; YukioNakamura; AkiraShibuya

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Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient KitW-sh/W-sh mice

机译：小鼠ES细胞衍生肥大细胞，MEDMC-BRC6，在肥大细胞缺陷的KITW-SH / W-SH小鼠中的长期存活

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摘要

An in-vitro-generated mast cell line that survives long-term in the skin

机译：体外产生的肥大细胞系，在皮肤中长期存活

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来源
《International immunology.》 |2017年第5期|共8页
作者
ShoheiShibagaki; SatokoTahara-Hanaoka; TakashiHiroyama; YukioNakamura; AkiraShibuya;
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作者单位

Department of Immunology Faculty of Medicine;

Department of Immunology Faculty of Medicine;

Cell Engineering Division RIKEN BioResource Center;

Cell Engineering Division RIKEN BioResource Center;

Department of Immunology Faculty of Medicine;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
degranulation; FcεRI; IgE-dependent anaphylaxis; TLR2; TLR4;

机译：脱粒;FcεR1;IgE依赖性过敏性;TLR2;TLR4;

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专利

1. Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient KitW-sh/W-sh mice [J] . ShoheiShibagaki, SatokoTahara-Hanaoka, TakashiHiroyama, International immunology. . 2017,第5期

机译：小鼠ES细胞衍生肥大细胞，MEDMC-BRC6，在肥大细胞缺陷的KITW-SH / W-SH小鼠中的长期存活
2. Mouse bone marrow-derived mast cells (mBMMC) obtained in vitro from mice that are mast cell-deficient in vivo express the same panel of granule proteases as mBMMC and serosal mast cells from their normal littermates. [J] . K K Eklund, N Ghildyal, K F Austen, The Journal of Experomental Medicine . 1994,第1期

机译：从体内缺乏肥大细胞的小鼠体外获得的小鼠骨髓来源的肥大细胞（mBMMC）与来自正常同窝小鼠的mBMMC和浆膜肥大细胞表达相同的一组颗粒蛋白酶。
3. Mast cell-deficient KitW-sh "sash" mutant mice display aberrant myelopoiesis leading to the accumulation of splenocytes that act as myeloid-derived suppressor cells [J] . MichelA., SchülerA., FriedrichP., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2013,第11期

机译：肥大细胞缺陷的KitW-sh“窗框”突变小鼠表现出异常的骨髓生成，导致脾细胞积聚，这些细胞起髓样来源的抑制细胞作用
4. SHORT-TERM TUMOR RESPONSE TO TYROSINE KINASE INHIBITORS VERSUS LONG-TERM SURVIVAL IN MAST CELL TUMORS: FOLLOW-UP DATA FROM A PIVOTAL FIELD STUDY WITH MASITINIB [C] . Olivier Hermine Annual Conference of the Veterinary Cancer Society . 2009

机译：短期肿瘤对酪氨酸激酶抑制剂的反应与肥大细胞肿瘤的长期存活：来自Masitinib的关键田间研究的后续数据
5. FATE OF BONE MARROW-DERIVED CULTURED MAST CELLS AFTER INTRACUT ANEOUS, INTRAPERITONEAL,AND INTRAVENOUS TRANSFER INTO GENETICALLY MAST CELL-DEFICIENT W/Wv MICE Evidence that Cultured Mast Cells Can Give Rise to Both Connective Tissue Type and Mucosal Mast [D] . 仲野, 徹 1988

机译：骨内源性，腹膜内和静脉内转移到遗传上缺乏乳腺的W / Wv小鼠后，骨髓来源的肥大细胞的命运证据表明，培养的肥大细胞可以使结缔组织类型和粘膜肥大同时上升
6. Mast Cell-Deficient W-sash c-kit Mutant KitW-sh/W-sh Mice as a Model for Investigating Mast Cell Biology in Vivo [O] . Michele A. Grimbaldeston, Ching-Cheng Chen, Adrian M. Piliponsky, 2005

机译：肥大细胞缺乏W窗框c-kit突变KitW-sh / W-sh小鼠作为体内研究肥大细胞生物学的模型
7. Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient KitW-sh/W-sh mice [O] . Shohei Shibagaki, Satoko Tahara-Hanaoka, Takashi Hiroyama, 2017

机译：小鼠ES细胞衍生的肥大细胞，MEDMC-BRC6，在肥大细胞缺陷的KITW-SH / W-SH小鼠中的长期存活

Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient KitW-sh/W-sh mice

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