KL-6 is not ineffective biomarker of indium lung

摘要

It has been reported that serum Krebs von den Lungen-6 (KL-6) (Kohno et al. 1989) is the most sensitive biomarker of indium-induced lung disease (Chonan et al. 2007; Hamaguchi et al. 2008; Nakano et al. 2009). In a previous report, Liu et al. (2012) noted that serum KL-6 was not elevated in indium tin oxide (ITO) processing workers and suggested that KL-6 may not be an appropriate indicator for evaluating the health of ITO workers. However, the KL-6 values reported in their paper are extremely different from those in our articles (Chonan et al. 2007; Hamaguchi et al. 2008; Nakano et al. 2009).