Human neutrophils are targets to paracoccin, a lectin expressed by Paracoccidioides brasiliensis

Ricci-Azevedo R.; Goncales R. A.; Roque-Barreira M. C.; Girard D.

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Human neutrophils are targets to paracoccin, a lectin expressed by Paracoccidioides brasiliensis

机译：人的中性粒细胞是裂藻蛋白的靶标，由帕拉基肽表达的凝集素

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Paracoccin (PCN), a lectin expressed by Paracoccidioides brasiliensis (Pb), is known to exert activities on the fungal biology, as well as different immune cells of myeloid origin. The aim of this study was to investigate the direct interaction of the recombinant form of the lectin (rPCN) with neutrophils, a neglected area.

机译：邻裂藻（PCN），已知由帕拉基肽（PB）表达的凝集素，以施加对真菌生物学的活性，以及骨髓原源的不同免疫细胞。本研究的目的是探讨凝集素（RPCN）的重组形式与中性粒细胞，被忽略的区域的直接相互作用。

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《Inflammation research: Official journal of the European Histamine Research Society》 |2018年第1期|共11页
作者
Ricci-Azevedo R.; Goncales R. A.; Roque-Barreira M. C.; Girard D.;
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作者单位

Univ Quebec Lab Rech Inflammat &

Physiol Granulocytes INRS Inst Armand Frappier 531 Boul;

Univ Sao Paulo Dept Biol Celular &

Mol Lab Glicobiol &

Imunoquim FMRP Ribeirao Preto SP Brazil;

Univ Sao Paulo Dept Biol Celular &

Mol Lab Glicobiol &

Imunoquim FMRP Ribeirao Preto SP Brazil;

Univ Quebec Lab Rech Inflammat &

Physiol Granulocytes INRS Inst Armand Frappier 531 Boul;

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原文格式 PDF
正文语种 eng
中图分类病理学;
关键词
Paracoccin; Immunomodulation; Neutrophils; Reactive oxygen species; Apoptosis;

机译：裂藻素;免疫调节;中性粒细胞;活性氧;细胞凋亡;

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1. Human neutrophils are targets to paracoccin, a lectin expressed by Paracoccidioides brasiliensis [J] . Ricci-Azevedo R., Goncales R. A., Roque-Barreira M. C., Inflammation research: Official journal of the European Histamine Research Society . 2018,第1期

机译：人的中性粒细胞是裂藻蛋白的靶标，由帕拉基肽表达的凝集素
2. Paracoccin, a GlcNAc-binding lectin from Paracoccidioides brasiliensis, binds to laminin and induces TNF-alpha production by macrophages. [J] . Coltri KC, Casabona Fortunato AS, Gennari Cardoso ML, Microbes and infection . 2006,第3期

机译：副球菌素（一种来自巴西副球菌的GlcNAc结合凝集素）与层粘连蛋白结合并诱导巨噬细胞产生TNF-α。
3. TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensis. [J] . Bonfim CV, Mamoni RL, Blotta MH Medical mycology: official publication of the International Society for Human and Animal Mycology . 2009,第7期

机译：巴西副球菌刺激的人单核细胞和中性粒细胞中TLR-2，TLR-4和dectin-1的表达。
4. Identification of Paracoccidioides brasiliensis by gold nanoprobes [C] . Jaciara F. S. Martins, Maiara L. Castilho, Maria A. G. Cardoso, Biomedical vibrational spectroscopy V: Advances in research and industry. . 2012

机译：纳米金探针鉴定巴西副球菌
5. Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes, and, Expression and function of the transient receptor potential 2 (TRPM2) ion channel in dendritic cells. [D] . Massullo, Pam. 2007

机译：与严重的先天性中性粒细胞减少症相关的G185R中性粒细胞弹性蛋白酶突变体的异常亚细胞靶向诱导分化的早幼粒细胞的过早凋亡，以及树突状细胞中瞬时受体电位2（TRPM2）离子通道的表达和功能。
6. The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells [O] . Nycolas Willian Preite, Claudia Feriotti, Dhêmerson Souza de Lima, -1

机译：Syk耦合的C型凝集素受体Dectin-2和Dectin-3参与人类浆细胞样树突状细胞识别巴西副球菌。
7. Paracoccin overexpression in Paracoccidioides brasiliensis reveals the influence of chitin hydrolysis on fungal virulence and host immune response [O] . Relber Aguiar Gonçales, Vanessa Cristina Silva Vieira, Rafael Ricci-Azevedo, 2019

机译：帕拉卡西菌素过度表达Brasiliensis揭示了几丁质水解对真菌毒力和宿主免疫应答的影响

Human neutrophils are targets to paracoccin, a lectin expressed by Paracoccidioides brasiliensis

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