Phytochemical analysis and antimicrobial evaluation of chloroform extracts of stem and roots of Scoparia dulcis L.

摘要

Natural compounds derived from medicinal plants serve as safe alternatives than conventional drugs in the treatment of various ailments, particularly microbial infections marred by Antibiotic resistance. In this context, we screened the common Liquorice weed, Scoparia dulcis L. for phytochemicals and antimicrobial potential. Phytochemical and HPTLC analysis of chloroform extracts of stem and roots of S. dulcis showed the presence of diversity of secondary metabolites. The extracts of the plant were assayed for antimicrobial activity in vitro against selected pathogenic bacteria and fungi. The results have shown the plant extracts to possess antibacterial and antifungal activities. The highest antibacterial activity exhibited by chloroform extract of the stem was against Staphylococcus aureus and roots against Escherichia. coll. The minimum inhibitory concentrations of stem and roots chloroform extracts (MIC, 150, 75 mg/mL of each) showed highest antibacterial and antifungal activities against E. coli and Asperigillus niger.