• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Asian Journal of Organic Chemistry >A Straightforward One‐Step Access to Ticlopidine Derivatives Arylated at the C5‐Position of the Thienyl Ring via Pd‐Catalyzed Direct Arylations
【24h】

A Straightforward One‐Step Access to Ticlopidine Derivatives Arylated at the C5‐Position of the Thienyl Ring via Pd‐Catalyzed Direct Arylations

机译：通过PD催化的直接芳基，对噻吩基环的C5位置施加在噻吩基环的C5位置的直接一步进入

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract > The reactivity of Ticlopidine, which belongs to the thienopyridine drug family, in Pd‐catalyzed C?H bond functionalization was investigated. The use of a palladium‐diphosphine catalyst associated to potassium acetate base in N , N ‐dimethylacetamide was found to promote the regioselective arylation at the C5‐position of the Ticlopidine thienyl ring with aryl bromides in high yields. In the course of this reaction, no dechlorination or debenzylation of the 2‐chlorobenzyl group of Ticlopidine was observed. A wide variety of substituents on the aryl bromide was tolerated, such as nitro, nitrile, acetyl, propionyl, benzoyl, ester, chloro, fluoro or trifluoromethyl. Bromopyridines and bromoquinolines were also successfully employed. This methodology gives a one‐step access to arylated Ticlopidine derivatives from commercially available compounds via a straightforward C?H bond functionalization procedure. Therefore, it provides a very appealing method to build a library of compounds containing a Ticlopidine unit. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>抽象</ title> > 研究了属于噻吩吡啶药物的噻氯丙胺的反应性，PD催化的C-H键官能化。使用与醋酸钾基础相关的钯 - 二膦催化剂 n </ i> 那 n </ i> - 发现 - 甲基乙酰胺在高产率高的芳基溴化物的C5-位置促进在噻吩甲基噻吩基环的C5位置处的区域选择性浓缩。在该反应过程中，观察到噻氯丙基的2-氯苄基的脱氯或脱苄酰基化。耐受芳基溴的各种取代基，例如硝基，腈，乙酰基，丙酰基，苯并，酯，氯，氟或三氟甲基。也成功地使用了溴吡啶和溴喹啉。该方法通过直接的C-H键官能化方法给出了从市售化合物的仲成噻吩啉衍生物的一步进入。因此，它提供了一种非常有吸引力的方法，用于构建含有噻吩啉单位的化合物库。 </ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-19765/'>《Asian Journal of Organic Chemistry》</a> <b style="margin: 0 2px;">|</b><span>2019年第11期</span><b style="margin: 0 2px;">|</b><span>共7页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Atoui Dhieb&option=202" target="_blank" rel="nofollow">Atoui Dhieb;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Haoran&option=202" target="_blank" rel="nofollow">Li Haoran;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ben Salem Ridha&option=202" target="_blank" rel="nofollow">Ben Salem Ridha;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Roisnel Thierry&option=202" target="_blank" rel="nofollow">Roisnel Thierry;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Soulé Jean‐Fran?ois&option=202" target="_blank" rel="nofollow">Soulé Jean‐Fran?ois;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Doucet Henri&option=202" target="_blank" rel="nofollow">Doucet Henri;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>CNRS ISCR-UMR 6226Univ RennesF-35000 Rennes France;</p> <p>CNRS ISCR-UMR 6226Univ RennesF-35000 Rennes France;</p> <p>Laboratoire de Chimie Organique LR 17ES08 Faculté des Sciences de SfaxUniversité de SfaxBP 1171 Route de la Soukra km 4 3038 Sfax Tunisia;</p> <p>CNRS ISCR-UMR 6226Univ RennesF-35000 Rennes France;</p> <p>CNRS ISCR-UMR 6226Univ RennesF-35000 Rennes France;</p> <p>CNRS ISCR-UMR 6226Univ RennesF-35000 Rennes France;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1184.html" title="有机化学">有机化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=catalysis&option=203" rel="nofollow">catalysis;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=palladium&option=203" rel="nofollow">palladium;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=C?H bond functionalization&option=203" rel="nofollow">C?H bond functionalization;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ticlopidine&option=203" rel="nofollow">Ticlopidine;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=arylation&option=203" rel="nofollow">arylation;</a> </p> <div class="translation"> 机译：催化;钯;C？H键官能化;噻丙酯;芳己; </div> </li> <li> <span class="lefttit">入库时间</span> <span>2022-08-20 01:29:16</span> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704022773556.html">A Straightforward One‐Step Access to Ticlopidine Derivatives Arylated at the C5‐Position of the Thienyl Ring via Pd‐Catalyzed Direct Arylations</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Atoui Dhieb&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Atoui Dhieb,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Haoran&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Li Haoran,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ben Salem Ridha&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ben Salem Ridha,</a> <a href="/journal-foreign-19765/" target="_blank" rel="nofollow" class="tuijian_authcolor">Asian Journal of Organic Chemistry .</a> <span>2019</span><span>,第11期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过PD催化的直接芳基，对噻吩基环的C5位置施加在噻吩基环的C5位置的直接一步进入</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704020339033.html">Assembling of medium long chain-based beta-arylated unnatural amino acid derivatives via the Pd(II)-catalyzed sp(3)beta-C-H arylation and a short route for rolipram-type derivatives</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Tomar Radha&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Tomar Radha,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bhattacharya Debabrata&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Bhattacharya Debabrata,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Babu Srinivasarao Arulananda&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Babu Srinivasarao Arulananda </a> <a href="/journal-foreign-30440/" target="_blank" rel="nofollow" class="tuijian_authcolor">Tetrahedron .</a> <span>2019</span><span>,第17期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过Pd（II）催化SP（3）β-C-H芳基化合物和Rolipram型衍生物的短途组装培养基的基于链基β-芳族化的非天然氨基酸衍生物</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-foreign_detail_thesis/0204113970878.html">Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp3)–H arylation</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yunyun Liu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yunyun Liu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yi Zhang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yi Zhang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xiaoji Cao&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xiaoji Cao,</a> <a href="/journal-foreign-15074/" target="_blank" rel="nofollow" class="tuijian_authcolor">Beilstein journal of organic chemistry. .</a> <span>2016</span><span>,第1期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过Pd催化的定向基团的一锅安装和C（sp3）–H芳基化反应合成β-芳基烷基酰胺</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-252588_thesis/0705010370091.html">Iron-Catalyzed Direct Arylation of 2-Arylpyridine Derivatives</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Naohiko Yoshikai&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Naohiko Yoshikai,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jakob Norinder&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Jakob Norinder,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Arimasa Matsumoto&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Arimasa Matsumoto </a> <a href="/conference-foreign-252588/" target="_blank" rel="nofollow" class="tuijian_authcolor">Symposium on Organometallic Chemistry .</a> <span>2008</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：铁催化的2-芳基吡啶衍生物的直接芳基</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/02061452292.html">Approaches to the total synthesis of (+/-)-pseudomonic acids. Model studies and reagent development in stereo- and regiocontrolled Pd-catalyzed alkylations and arylations of allylic alcohol derivatives.</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Brescia, Marc-Raleigh.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Brescia, Marc-Raleigh. </a> <span>1997</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：（+/-）-假单仲酸的全合成方法。立体和区域控制的Pd催化烯丙基醇衍生物的烷基化和芳基化的模型研究和试剂开发。</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040003500791.html">Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp3)–H arylation</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yunyun Liu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yunyun Liu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yi Zhang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yi Zhang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xiaoji Cao&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xiaoji Cao,</a> <span>2016</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过Pd催化的定向基团的一锅安装和C（sp3）–H芳基化反应合成β-芳基烷基酰胺</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/0100095505147.html ">Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp<sup>3</sup>)–H arylation</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yunyun Liu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yunyun Liu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yi Zhang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yi Zhang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xiaoji Cao&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xiaoji Cao,</a> <span>2016</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过pd催化的一锅装置引导基团和C（sp <sup> 3 </ sup>）-H芳基化合成β-芳基化烷基酰胺</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_applied-chemical-industry_thesis/0201248422071.html">Pd(OAc)2/CuI共催化杂环C—H键与芳基溴的直接芳基化反应研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=颜雪明&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 颜雪明</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=肖新荣&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,肖新荣</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=谭倪&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,谭倪</a> <span> <a href="/journal-cn-9217/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 应用化工 </a> </span> <span> . 2012</span><span>,第008期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_university-chemistry_thesis/0201229435694.html">芳基离子及芳基自由基与环己二烯离子及环己二烯自由基的区别</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=许家喜&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 许家喜</a> <span> <a href="/journal-cn-10553/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 大学化学 </a> </span> <span> . 2013</span><span>,第003期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chemical-journal-chinese-universities_thesis/0201231593541.html">由二茂铁亚胺环钯催化的Suzuki偶联反应合成具有发光性能的3-芳基噻吩</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张金莉&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 张金莉</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=吴养洁&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,吴养洁</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李敬亚&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李敬亚</a> <span> <a href="/journal-cn-10958/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 高等学校化学学报 </a> </span> <span> . 2007</span><span>,第012期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-university-south-china-science-technology_thesis/0201270223492.html">无膦配体双金属共催化唑类杂环与芳基碘的直接芳基化研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=颜雪明&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 颜雪明</a> <span> <a href="/journal-cn-4674/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 南华大学学报（自然科学版） </a> </span> <span> . 2018</span><span>,第006期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-organic-chemistry_thesis/0201291995347.html">铜盐催化下杂环与芳基溴的直接C-芳基化反应:荧光核心骨架的发现</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . </a> <span> <a href="/journal-cn-15847/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 有机化学 </a> </span> <span> . 2009</span><span>,第6期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-67038_thesis/020223029822.html">环八四噻吩及其芳基化与树枝状衍生物的AIE现象</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=杨玉杰&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 杨玉杰</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=赵春梅&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,赵春梅</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王鹏飞&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,王鹏飞</a> <span> <a href="/conference-cn-67038/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 全国第十九届大环化学暨第十一届超分子化学学术讨论会 </a> <span> <span> . 2018</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020316246719.html">基于噻吩/硒吩基并三芳杂环的非对称有机半导体材料及“S”型双螺烯的合成</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王萌杰&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王萌杰</a> <span> . 2020</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06120106457984.html">6-环氨基-2-噻吩基-3-(吡啶-4-基)咪唑并1,2-b哒嗪和6-环氨基-2-呋喃基-3-(吡啶-4-基)咪唑并1,2-b哒嗪的衍生物,其制备和治疗用途</a> <b>[P]</b> . <span> 中国专利： CN102256979A </span> <span> . 2011-11-23</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120107447491.html">取代的1-(芳基乙炔基)双环链烷醇、1-(杂芳基乙炔基)双环链烷醇、1-(杂环基乙炔基)双环链烷醇和1-(环烯基乙炔基)双环链烷醇作为对抗非生物植物胁迫的活性剂的用途</a> <b>[P]</b> . <span> 中国专利： CN104955327A </span> <span> . 2015-09-30</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130499563632.html">SYNTHESIS OF FT4-BASED ORGANIC SEMICONDUCTING SMALL MOLECULES BY PD-CATALYZED DIRECT (HETERO)ARYLATION OR DIRECT ALKENYLATION</a> <b>[P]</b> . <span> 外国专利： <!-- --> US2021074930A1 </span> <span> . 2021-03-11</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过PD催化直接（杂）芳基化或直接链烯化合成FT4基有机半导体小分子 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130446737613.html">Process for the one-step direct alkylation, in positions 7 and 10 simultaneously of the two hydroxy functions on 10-deacetylbaccatin (of the taxoid family) or on derivatives thereof which are esterified in position 13</a> <b>[P]</b> . <span> 外国专利： <!-- --> NZ504125A </span> <span> . 2002-10-25</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：在10-去乙酰基浆果赤霉素（紫杉烷类）或其衍生物上在13位酯化的两个羟基官能团同时在7和10位进行一步一步直接烷基化的方法 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130450887640.html">Direct alkylation process, in a single step, in position 7 and 10 simultaneously of the two hydroxyl functions of 10-deacetylbaccatin or derivatives of the latter in position 13</a> <b>[P]</b> . <span> 外国专利： <!-- --> BR9814658A </span> <span> . 2000-10-03</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：在10位脱乙酰浆果赤霉素或其衍生物在13位的两个羟基官能团同时在7位和10位进行直接烷基化过程 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704022773556','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> <div class="journal-sub"> <h2>期刊订阅</h2> <img src="https://cdn.zhangqiaokeyan.com/img/loginclose.png" alt="" onclick="$('.journalsub-pop-up').hide()"> <p class="pardon">抱歉，该期刊暂不可订阅，敬请期待！</p> <p class="current">目前支持订阅全部北京大学中文核心（2020）期刊目录。</p> <div style="display: flex;margin-top: 69px;justify-content: space-between;"> <div class="no-sub" onclick="$('.journalsub-pop-up').hide()">暂不订阅</div> <div class="other-sub" onclick="continueSub('from=pc-detail')">继续订阅其他期刊</div> </div> </div> </div> <div class="right_btn"> <ul> <li class="gouwuche"> <!-- <a href="javascript:void(0);" onclick="link_analysis('/shoppingcart/auth/list.html',this)">购物车</a>--> </li> <li class="yijian"> <a href="javascript:void(0);" onclick="link_analysis('/mycenter/auth/complaint.html',this)">意见反馈</a> </li> <li class="top"> <a href="javascript:scrollTo(0,0);">回到顶部</a> </li> <li class="shouye"> <a href="/">回到首页</a> </li> </ul> </div> <div class="xllindexfooter"> <div class="xllindexfootercenter"> <div class="xllindexfooterleft left" > <div class="xllindexfooterleftli"> <ul> <li><a href="/about.html">关于掌桥</a></li> <li><a href="/help/helpmap.html">资源导航</a></li> <li><a href="/help/helpguide.html">新手指南</a></li> <li><a href="/help/helpcenter.html">常见问题</a></li> <li><a href="/sitemap.html">网站地图</a></li> <li><a href="/help/helpcenter.html?type=9">版权声明</a></li> </ul> </div> <div class="xllindexfooterleft"> <p class="xllindexfooterlefteamil">客服邮箱：kefu@zhangqiaokeyan.com</p> <div class="xllindexfooterlefttcp"> <div class="xllindexfooterpoliceiimg"></div> <div class="xllindexfooterpoliceispan"> <span>京公网安备：11010802029741号 </span> <span>ICP备案号：<a href="https://beian.miit.gov.cn" rel="nofollow" target="_blank">京ICP备15016152号-6</a></span> <span>六维联合信息科技 (北京) 有限公司©版权所有</span> </div> </div> </div> </div> <div class="xllindexfooterright left"> <ul> <li> <p style="font-weight: bold;">客服微信</p> <div></div> </li> <li> <p style="font-weight: bold;">服务号</p> <div></div> </li> </ul> </div> </div> </div> <span id="0704022773556down" data-source="7," data-out-id="kW0XwoWcJ/EsMqsr1+aShriZPuqqF0HfpwUKWOon1k6GdQTeNm2TQf/4FnfMsmYY," data-f-source-id="7" data-title="A Straightforward One‐Step Access to Ticlopidine Derivatives Arylated at the C5‐Position of the Thienyl Ring via Pd‐Catalyzed Direct Arylations" data-price="20" data-site-name="" data-transnum="24" style="display:none;"></span> <input type="hidden" value="4" id="sourcetype"> <input type="hidden" value="19765" id="journalid"> <input type="hidden" value="https://cdn.zhangqiaokeyan.com" id="imgcdn"> <input type="hidden" value="1" id="isdeatail"> <input type="hidden" value="" id="syyn_indexed_database"> <input type="hidden" value="" id="servicetype"> <input type="hidden" id="pagename" value="A Straightforward One‐Step Access to Ticlopidine Derivatives Arylated at the C5‐Position of the Thienyl Ring via Pd‐Catalyzed Direct Arylations"/> <input type="hidden" value="thesis_get_original" id="pageIdentification"> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery-1.12.4.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/lwlh_ajax.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zq.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/common.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery.cookie.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/top.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/tip.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/login.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/down.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/search.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/searchtype.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/user/regist.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zxs_solor/detail.js?v=5.7.6"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/statistics/static/pagecollection.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/tj.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/pushbaidu.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/history.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/util/cookie.js?v=5.7.6"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/weipu/weipu.js?v=5.7.6"></script> </body> <script> $(function(){ var weiPuStatus = getCookie('WeiPuStatus'); if(weiPuStatus){ tipWeiPuStatus(weiPuStatus); delCookie('WeiPuStatus'); } getFacetKeywordVoInId(); var sourcetype = $("#sourcetype").val(); if(sourcetype ==1||sourcetype==4){ getJournal(); } }) </script> </html>