Patient-Reported Outcomes and the Association With Clinical Response in Patients With Active Psoriatic Arthritis Treated With Golimumab: Findings Through 2 Years of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Kavanaugh Arthur; McInnes Iain B.; Krueger Gerald G.; Gladman Dafna; Beutler Anna; Gathany Tim; Mack Michael; Tandon Neeta; Han Chenglong; Mease Philip

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Patient-Reported Outcomes and the Association With Clinical Response in Patients With Active Psoriatic Arthritis Treated With Golimumab: Findings Through 2 Years of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

机译：患者报告的结果和与Golimumab治疗的活性银屑病关节炎患者临床反应的关联：通过2年的III，多中心，随机，双盲，安慰剂对照试验

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Objective. To evaluate the effect of golimumab on physical function, health-related quality of life (HRQOL), and productivity in psoriatic arthritis (PsA).

机译：客观的。评估Golimalab对物理功能，与健康相关质量（HRQOL）的影响，以及银屑病关节炎（PSA）的生产力。

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《Arthritis care & research》 |2013年第10期|共8页
作者
Kavanaugh Arthur; McInnes Iain B.; Krueger Gerald G.; Gladman Dafna; Beutler Anna; Gathany Tim; Mack Michael; Tandon Neeta; Han Chenglong; Mease Philip;
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作者单位

Univ Calif San Diego La Jolla CA 92093 USA;

Univ Glasgow Glasgow Lanark Scotland;

Univ Utah Hlth Sci Ctr Salt Lake City UT USA;

Toronto Western Hosp Toronto ON M5T 2S8 Canada;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Global Serv LLC Malvern PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Pharmaceut Titusville NJ USA;

Janssen Global Serv LLC Malvern PA USA;

Swedish Med Ctr Seattle WA USA;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
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1. Patient-Reported Outcomes and the Association With Clinical Response in Patients With Active Psoriatic Arthritis Treated With Golimumab: Findings Through 2 Years of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial [J] . Kavanaugh Arthur, McInnes Iain B., Krueger Gerald G., Arthritis care & research . 2013,第10期

机译：患者报告的结果和与Golimumab治疗的活性银屑病关节炎患者临床反应的关联：通过2年的III，多中心，随机，双盲，安慰剂对照试验
2. Erratum: Golimumab, a human anti-tumor necrosis factor monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: Twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis [J] . li id=au1Paul Emery li id=au2Roy M. Fleischmann li id=au3Larry W. Moreland li id=au4Elizabeth C. Hsia li id=au5Ingrid Strusberg li id=au6Patrick Durez li id=au7Peter Nash li id=au8Eric Jason B. Amante li id=au9Melvin Churchill li id=au10Won Park li id=au11Bernardo Antonio Pons-Estel li id=au12Mittie K. Doyle li id=au13Sudha Visvanathan li id=au14Weichun Xu li id=au15Mahboob U. Rahman Arthritis & Rheumatism . 2010,第9期

机译：勘误：Golimumab，一种人类抗肿瘤坏死因子单克隆抗体，每隔四周皮下注射一次未接受甲氨蝶呤的活动性类风湿性关节炎患者：三期，多中心，随机，双盲，安慰剂治疗二十三周的结果氨甲蝶呤前戈利木单抗作为早期治疗类风湿关节炎的一线治疗的对照研究
3. Golimumab, a Human Anti-Tumor Necrosis Factor alpha Monoclonal Antibody, Injected Subcutaneously Every Four Weeks in Methotrexate-Naive Patients With Active Rheumatoid Arthritis Twenty-Four-Week Results of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Golimumab Before Methotrexate as First-Line Therapy for Early-Onset Rheumatoid Arthritis (vol 60, pg 2272, 2009) [J] . Emery Arthritis and Rheumatism . 2010,第9期

机译：Golimumab是一种人类抗肿瘤坏死因子α单克隆抗体，每四周一次皮下注射纯净甲氨蝶呤的活动性类风湿性关节炎患者，III期，多中心，随机，双盲，安慰剂对照研究的二十四周结果甲氨tre呤之前戈利木单抗作为早期治疗类风湿关节炎的一线治疗方法的研究（第60卷，第2272页，2009年）
4. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
5. Patient-Reported Outcomes and the Association With Clinical Response in Patients With Active Psoriatic Arthritis Treated With Golimumab: Findings Through 2 Years of a Phase III Multicenter Randomized Double-Blind Placebo-Controlled Trial [O] . Arthur Kavanaugh, Iain B McInnes, Gerald G Krueger, -1

机译：戈利木单抗治疗活动性银屑病关节炎患者的结果报告及与临床反应的关联：通过2年III期多中心随机双盲安慰剂对照试验的结果
6. Golimumab, a human anti–tumor necrosis factor monoclonal antibody, injected subcutaneously every 4 weeks in patients with active rheumatoid arthritis who had never taken methotrexate: 1-year and 2-year clinical, radiologic, and physical function findings of a phase III, multicenter, randomized, double-blind, placebo-controlled study. [O] . Emery, Paul, Fleischmann, Roy M, Doyle, Mittie K, 2013

机译：Golimumab是一种人类抗肿瘤坏死因子单克隆抗体，每4周皮下注射一次从未服用过甲氨蝶呤的活动性类风湿关节炎患者：III期，多中心的1年和2年临床，影像学和身体功能检查结果，随机，双盲，安慰剂对照研究。

Patient-Reported Outcomes and the Association With Clinical Response in Patients With Active Psoriatic Arthritis Treated With Golimumab: Findings Through 2 Years of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

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