Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial

Tjarnlund Anna; Tang Quan; Wick Cecilia; Dastmalchi Maryam; Mann Herman; Studynkova Jana Tomasova; Chura Radka; Gullick Nicola J.; Salerno Rosaria; Ronnelid Johan; Alexanderson Helene; Lindroos Eva; Aggarwal Rohit; Gordon Patrick; Vencovsky Jiri; Lundberg Ingrid E.

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Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial

机译：Abatacept在成人皮塔米肌炎和多膜质的治疗中：随机，相IIB治疗延迟开始试验

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Objectives To study the effects of abatacept on disease activity and on muscle biopsy features of adult patients with dermatomyositis (DM) or polymyositis (PM).

机译：研究AbataCept对疾病活动和Dermatyistis（DM）或多发性肌炎（PM）患者肌肉活检特征的影响。

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来源
《Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research》 |2018年第1期|共8页
作者
Tjarnlund Anna; Tang Quan; Wick Cecilia; Dastmalchi Maryam; Mann Herman; Studynkova Jana Tomasova; Chura Radka; Gullick Nicola J.; Salerno Rosaria; Ronnelid Johan; Alexanderson Helene; Lindroos Eva; Aggarwal Rohit; Gordon Patrick; Vencovsky Jiri; Lundberg Ingrid E.;
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作者单位

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

Inst Rheumatol Dept Rheumatol Prague Czech Republic;

Inst Rheumatol Dept Rheumatol Prague Czech Republic;

Kings Coll Hosp NHS Fdn Trust Dept Rheumatol London England;

Kings Coll Hosp NHS Fdn Trust Dept Rheumatol London England;

Kings Coll Hosp NHS Fdn Trust Dept Rheumatol London England;

Uppsala Univ Dept Immunol Genet &

Pathol Uppsala Sweden;

Karolinska Inst Dept Neurobiol Div Physiotherapy Stockholm Sweden;

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

Univ Pittsburgh Sch Med Div Rheumatol &

Clin Rheumatol Pittsburgh PA USA;

Kings Coll Hosp NHS Fdn Trust Dept Rheumatol London England;

Inst Rheumatol Dept Rheumatol Prague Czech Republic;

Karolinska Inst Karolinska Univ Hosp Dept Med Rheumatol Unit Stockholm Sweden;

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正文语种 eng
中图分类免疫性疾病;
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专利

1. Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial [J] . Tjarnlund Anna, Tang Quan, Wick Cecilia, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2018,第1期

机译：Abatacept在成人皮塔米肌炎和多膜质的治疗中：随机，相IIB治疗延迟开始试验
2. Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis [J] . Tang Quan, Ramskold Daniel, Krystufkova Olga, Scandinavian journal of immunology. . 2019,第1期

机译：CTLA4-Ig（Abatacept）治疗在多岩肌炎患者外周血中T细胞和B细胞的影响
3. Effect of abatacept treatment on T cells in peripheral blood and muscle tissue in polymyositis and dermatomyositis patients [J] . Tang Quan, Ramskold Daniel, Krystufkova Olga, Scandinavian journal of immunology. . 2017,第4期

机译：AbataCept治疗对多发性和皮肤病患者外周血和肌肉组织中T细胞的影响
4. Laser Therapy in the Treatment of Achilles Tendinopathy: A Randomised Controlled Trial [C] . Steve Tumilty MPhty, Joanne Munn PhD, J. Haxby Abbott PhD, International Laser Medicine Congress . 2010

机译：激光治疗治疗Achilles肌腱病变：随机对照试验
5. Nutritional Risk in the Cancer Patient 65 and Older Undergoing Systemic Treatment via Phase I Clinical Trials [D] . Williams, Anna Cathy. 2019

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6. Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis and Adult Polymyositis: A Randomized Placebo-phase Trial [O] . Chester V. Oddis, Ann M. Reed, Rohit Aggarwal, -1

机译：利妥昔单抗难治成人和儿童皮肌炎和多发性肌炎成人的治疗：一项随机安慰剂相试用
7. Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: Twelve-month results of a phase IIb, double-blind, randomized, placebo-controlled trial [O] . Kremer Joel J.M., Dougados Maxime M., Emery Paul, 2005

机译：用选择性共刺激调节剂阿巴西普治疗类风湿关节炎：IIb期，双盲，随机，安慰剂对照试验的十二个月结果

Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial

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