Treatment of iron deficiency and iron deficiency anemia with intravenous ferric carboxymaltose in pregnancy

摘要

BackgroundIron deficiency (ID) and iron deficiency anemia (IDA) in pregnancy are global health issues, affecting around 30% of women in high-resourced countries, and increasing to over 50% of women in low-resourced countries.ObjectivesFroessler et al. study published in Archives of Gynecology and Obstetrics (2018) 298: 75. 10.1007/s00404-018-4782-9, raised many queries and we would like to know the answers of those queries from the authors if possible.ResultsDiagnosis of IDA should be based on hemoglobin concentration (gm/dl), serum ferritin (ug/l), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH), and the efficacy of the treatment of IDA evaluated by comparing pre-treatment values of hemoglobin, serum ferritin, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) by the post-treatment values. Parenteral iron dose for correction of IDA calculated according to the formula; total iron needed in mg=2.4xpre-pregnancy weight in kgx(target hemoglobin concentration-actual hemoglobin concentration)gm/dl+500mg.ConclusionThe efficacy of the treatment of IDA evaluated by comparing pre-treatment values of hemoglobin, serum ferritin, MCV, and MCH by the post-treatment values. Parenteral iron dose for correction of IDA calculated according to the formula; total iron needed in mg=2.4+pre-pregnancy weight in kg+(target hemoglobin concentration-actual hemoglobin concentration) gm/dl+500mg.