A Box-Behnken Optimized Methodology for the Quantification of Diclofenac using a Carbon Paste-Multiwalled Carbon Nanotubes Electrode

摘要

Background: Diclofenac is a widely used nonsteroidal anti-inflammatory drug. Recent studies have shown that frequent consumption of this drug in high concentrations can cause heart diseases, so strict control of diclofenac's quantity in commercial drugs is necessary. This paper presents the development of an optimized voltammetric methodology for the quantification of diclofenac, which offers some advantages over other electrochemical and accepted methods.