Antimicrobial Preservatives Part Three: Challenges Facing Preservative Systems

摘要

The third and final article in this series deals with the many external challenges that face formulators who are developing preservation systems for multi-use oral, topical and parenteral medicinal products. This article provides current perspectives on safety, regulatory, public relations issues. Mention is also made, where relevant of uses of antimicrobial agents in activities such as disinfection procedures and in non-pharmaceutical products. Two case studies are presented to highlight the very real issues encountered when trying to preserve multi-use pharmaceutical products.