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The study by Slotty and colleagues must be commended for some of the information provided. Although other studies on the topic are available, the authors correctly measured the shift of the target points instead of using surrogate measures such as the shift of the intercom-misural line. The authors demonstrate that the shift was clinically irrelevant. Brain shift due to CSF loss has early been recognized as an important source of error in deep brain stimulation surgery. Even though a negative effect on the precision of the procedure is undeniable, its real clinical importance is, in my opinion, relative. This is demonstrated by the high rate of efficacy of deep brain stimulation (DBS) for movement disorders with failures mainly ascribable to errors in patients' selection. With the current technique, it is possible to quickly insert cannulas along the selected trajectory immediately after a burr hole has been performed. Cannulas that serve to guide the microelectrode rigidly fix the brain, at least in the zone close to the target. More importantly, minimal shift due to CSF leakage are easily and reliably corrected using microelectrode recordings. This is an invaluable tool in confirming the target. This technique has contributed to the dramatic improvements that many patients have experienced with a wide array of stereotactic procedures. Nevertheless, postoperative pneumocephalus is a possible troubling complication of bilateral and long-lasting procedure such as DBS. Using burr hole sealants is a smart solution to avoid excessive CSF loss.
机译:Slotty及其同事所做的研究必须为所提供的某些信息所称赞。尽管可以进行有关该主题的其他研究,但是作者正确地测量了目标点的位移,而不是使用替代措施(例如,导管间线的位移)。作者证明,这种转变在临床上无关紧要。早已认识到由于脑脊液流失引起的脑转移是深部脑刺激手术中错误的重要来源。尽管对手术精度的负面影响是不可否认的,但在我看来,其真正的临床重要性却是相对的。深部脑刺激(DBS)对运动障碍,主要归因于患者选择错误的失败的高效率证明了这一点。利用当前的技术,可以在已经执行了毛刺孔之后立即沿着选定的轨迹快速插入套管。用来引导微电极的插管至少在靠近目标的区域内将大脑刚性固定。更重要的是,使用微电极记录可以轻松,可靠地校正由于CSF泄漏引起的最小位移。这是确定目标的宝贵工具。这项技术极大地改善了许多患者在各种立体定向手术中所经历的状况。然而,术后气肺可能是双侧和长期手术(如DBS)的令人困扰的并发症。使用毛刺孔密封剂是避免过多CSF损失的明智解决方案。

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