Phase II Study of Neoadjuvant Chemotherapy With S-1 and CDDP in Patients With Lymph Node Metastatic Stage II or III Gastric Cancer

Kochi Mitsugu; Fuji Masashi; Kanamori Noriaki; Mihara Yoshiaki; Funada Tomoya; Tamegai Hidenori; Watanabe Megumu; Takayama Yuriko; Suda Hiroshi; Takayama Tadatoshi

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Phase II Study of Neoadjuvant Chemotherapy With S-1 and CDDP in Patients With Lymph Node Metastatic Stage II or III Gastric Cancer

机译：淋巴结转移阶段II或III胃癌患者患有S-1和CDDP的Neoadjuvant化疗的II期研究

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Objectives: We conducted a phase II trial to investigate the efficacy and safety of neoadjuvant chemotherapy (NAC) comprising S-1 and cisplatin (CDDP) followed by extensive resection in the management of resectable locally advanced gastric cancer with lymph node (LN) metastases.

机译：目的：我们进行了一项第二阶段试验，以研究新辅助化疗（NAC）的疗效和安全性，然后在与淋巴结（LN）转移的可重置局部晚期胃癌中进行广泛切除。

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来源
《American Journal of Clinical Oncology: Cancer Clinical Trials》 |2017年第1期|共5页
作者
Kochi Mitsugu; Fuji Masashi; Kanamori Noriaki; Mihara Yoshiaki; Funada Tomoya; Tamegai Hidenori; Watanabe Megumu; Takayama Yuriko; Suda Hiroshi; Takayama Tadatoshi;
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作者单位

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

Nihon Univ Sch Med Dept Digest Surg Tokyo Japan;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
gastric cancer; preoperative chemotherapy; prognosis; S-1; CDDP;

机译：胃癌;术前化疗;预后;S-1;CDDP;
入库时间 2022-08-20 00:47:57

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专利

1. Phase II Study of Neoadjuvant Chemotherapy With S-1 and CDDP in Patients With Lymph Node Metastatic Stage II or III Gastric Cancer [J] . Kochi Mitsugu, Fuji Masashi, Kanamori Noriaki, American Journal of Clinical Oncology: Cancer Clinical Trials . 2017,第1期

机译：淋巴结转移阶段II或III胃癌患者患有S-1和CDDP的Neoadjuvant化疗的II期研究
2. A Comparison of Multimodality Treatment: Two and Four Courses of Neoadjuvant Chemotherapy Using S-1/CDDP or S-1/CDDP/Docetaxeln Followed by Surgery and S-1 Adjuvant Chemotherapy for Macroscopically Resectable Serosa-positive Gastric Cancer: A Randomizedn Phase II Trial (COMPASS-D Trial) [J] . Akira Tsuburaya Japanese Journal of Clinical Oncology . 2012,第1期

机译：多模式治疗的比较：使用S-1 / CDDP或S-1 / CDDP / Docetaxeln进行新辅助化疗的两个和四个疗程，然后进行手术和S-1辅助化疗用于宏观可切除的浆膜阳性胃癌：II期随机试验（COMPASS-D试用）
3. Phase II trial of neoadjuvant chemotherapy with intraperitoneal paclitaxel, S-1, and intravenous cisplatin and paclitaxel for stage IIIA or IIIB gastric cancer [J] . Shinkai Masayuki, Imano Motohiro, Chiba Yasutaka, Journal of Surgical Oncology . 2019,第1期

机译：Neoadjuvant化疗的II期试验用腹膜内紫杉醇，S-1和静脉内顺铂和紫杉醇术治疗IIIA期或IIIB胃癌
4. S-1/CDDP/Lentinan Combination Chemotherapy for Inoperable Advanced Gastric Cancer [C] . Shoichi Nagahashi, Hidekazu Suzuki, Toshifumi Hib International Gastric Cancer Congress . 2005

机译：S-1 / CDDP / Lentinan组合化疗，可管理的胃癌无法操作
5. The effectiveness of chemoradiation for stage III non-small-cell lung cancer patients at the Kingston Regional Cancer Center (Ontario). [D] . Sinclair, Suzanne Marie. 2003

机译：金斯敦地区癌症中心（安大略省）对III期非小细胞肺癌患者进行化学放射治疗的有效性。
6. The protocol of a prospective multicenter randomized controlled phase III study evaluating different cycles of oxaliplatin combined with S-1 (SOX) as neoadjuvant chemotherapy for patients with locally advanced gastric cancer: RESONANCE-II trial [O] . Xinxin Wang, Shuo Li, Yihong Sun, 2021

机译：评估当地晚期胃癌患者的欧洲蛋白和S-1（SOX）与S-1（SOX）相结合的不同循环的预期多中心随机的控制阶段III研究的议定书评估作为Neoadjuvant化疗：共鸣-II试验
7. A phase II study of neoadjuvant chemotherapy with docetaxel, cisplatin, and S-1, followed by gastrectomy with D2 lymph node dissection for high-risk advanced gastric cancer: results of the KDOG1001 trial [O] . Kei Hosoda, Mizutomo Azuma, Chikatoshi Katada, 2018

机译：Neoadjuvant化疗与多西紫杉醇，顺铂和S-1的II期研究，随后用D2淋巴结解剖胃切除术治疗高危高危胃癌：KDOG1001试验的结果

Phase II Study of Neoadjuvant Chemotherapy With S-1 and CDDP in Patients With Lymph Node Metastatic Stage II or III Gastric Cancer

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