Agranulocytosis Associated with Waldenstr?m Macroglobulinemia

摘要

Currently, there are only 2 case reports of Waldenstr?m macroglobulinemia (WM) associated with severe neutropenia. This is a case report of a woman with a past medical history of WM who presented with neutropenic fever. The patient’s febrile neutropenia resolved after RCD chemotherapy (cyclophosphamide 750 mg/m~(2), dexamethasone 20 mg, and rituximab 375 mg/m~(2)). Fourteen days after administration, the neutrophil level had started to rise and normalized after 6 days. To the best of our knowledge, this is the 3rd reported case of agranulocytosis due to WM.