Lsing LICHeE and BAMSE forReconstructing Cancer Phylogenetic Trees

摘要

The reconstruction of cancer phylogeny trees and quantifying the evolution ofthe disease is a challenging task. LICHeE and BAMSE are two computationaltools designed and implemented recently for this purpose. They both utilizeestimated variant allele fraction of somatic mutations acrossmultiple samples toinfer the most likely cancer phylogenies. This unit provides extensive guidelinesfor installing and running both LICHeE and BAMSE.