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Selective Estrogen Receptor Modulators (SERMs): Mechanistic Insights Against Microbial Infections

机译:选择性雌激素受体调节剂(SERMS):针对微生物感染的机械洞察力

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摘要

Background: Infections are one of the leading causes of death worldwide and currently available treatments remain unsatisfactory due to rise in the cases of antimicrobial resistance. Thus, there is a need for the development of new drugs with different mechanisms of action. However, the development of new antimicrobials agents is a long and expensive process. Hence, most of the pharmaceutical companies are looking forward to repurposing the already available drugs against microbial infections.
机译:背景:感染是全世界领先的死亡原因之一,目前可用的治疗仍然在抗微生物抵抗病例上升时仍然不满意。 因此,需要具有不同的作用机制的新药。 然而,新的抗微生物剂的发展是一种漫长而昂贵的过程。 因此,大多数制药公司期待将已有的药物用于对微生物感染的可用药物进行重新培训。

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