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Extended cardiac ambulatory rhythm monitoring in adults with congenital heart disease: Arrhythmia detection and impact of extended monitoring

机译:具有先天性心脏病的成年人的扩展心动动态节律监测:心律失常检测和扩展监测的影响

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Abstract Background Arrhythmias are a leading cause of death in adults with congenital heart disease (ACHD). While 24‐48‐hour monitors are often used to assess arrhythmia burden, extended continuous ambulatory rhythm monitors (ECAM) can record 2 weeks of data. The utility of this device and the arrhythmia burden identified beyond 48‐hour monitoring have not been evaluated in the ACHD population. Additionally, the impact of ECAM has not been studied to determine management recommendations. Objective To address the preliminary question, we hypothesized that clinically significant arrhythmias would be detected on ECAM beyond 48?hours and this would lead to clinical management changes. Methods A single center retrospective cohort study of ACHD patients undergoing ECAM from June 2013 to May 2016 was performed. The number and type of arrhythmias detected within and beyond the first 48?hours of monitoring were compared using Kaplan‐Meier curves and Cox proportional hazard models. Results Three hundred fourteen patients had monitors performed [median age 31 (IQR 25‐41) years, 61% female). Significant arrhythmias were identified in 156 patients (50%), of which 46% were noted within 48 hours. A management change based on an arrhythmia was made in 49 patients (16%). Conclusions ECAM detects more clinically significant arrhythmias than standard 48‐hour monitoring in ACHD patients. Management changes, including medication changes, further testing or imaging, and procedures, were made based on results of ECAM. Recommendations and guidelines have been made based on arrhythmias on 48‐hour monitoring; the predictive ability and clinical consequence of arrhythmias found on ECAM are not yet known.
机译:摘要背景心律失常是先天性心脏病(ACHD)成人死亡的主要原因。虽然24-48小时的监视器通常用于评估心律失常负担,但延长的连续动态节奏监视器(ECAM)可以记录2周的数据。在ACHD人口中尚未评估该装置的效用和确定超过48小时监测的心律失常负担。此外,尚未研究ECAM的影响以确定管理层建议。目的旨在解决初步问题,我们假设临床上显着的心律失常将在48岁以下的Ecam上检测到eCAM?小时,这将导致临床管理变化。方法对2013年6月至2016年5月开始的ACHD患者的单一中心回顾队伍研究于2016年5月至2016年5月。使用Kaplan-Meier曲线和Cox比例危险模型比较了在前48岁及以上检测到的前48小时内和超越的心律失常的数量和类型。结果三百四四名患者进行了监视器[中位年龄31(IQR 25-41)年,女性61%)。在156名患者(50%)中确定了显着的心律失常,其中46%在48小时内注意到。 49名患者(16%)提出了基于心律失常的管理变化。结论Ecam检测在ACHD患者中的标准48小时监测中的更高临床显着的心律失常。管理变更,包括药物改变,进一步的测试或成像以及程序,是基于Ecam的结果制定的。建议和准则基于48小时监测的心律失常; Ecam发现的预测能力和临床后果尚不清楚。

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