Two cases of prenatally diagnosed sacrococcygeal teratoma type I with different clinical features

摘要

Sacrococcygeal teratoma (SCT) is a rare congenital disease and prognostic factors have not been entirely established. We report two cases of fetal SCT with different clinical courses. Case 1 was a cystic, slow growing tumor with mild vascularity. The tumor was removed one week after delivery at 35 weeks, and there was no recurrence at 1.5-year follow-up. Case 2 was a solid, rapid growing tumor with rich vascularity. Cesarean section was performed due to severe fetal hydrops and mirror syndrome in the mother at 27 weeks. The tumor had ruptured and was removed soon after delivery to control bleeding, but the baby died the next day. Our cases suggest that solid component and rich vascularity might correlate with poor prognosis. Sacrococcygeal teratoma (SCT) is a rare congenital disease of the newborn, with an estimated prevalence of 1 in 20 000-40 000 pregnancies with a female predominance at a ratio of 3:1. SCT arises from pleuripotential embryonic cells of the coccyx. It requires close in utero surveillance due to unpredictable growth and physiologic effects (Wilson RD et al. 2009). Many prognostic factors have been evaluated but a complete algorithm for the perinatal management of prenatally diagnosed SCT is not complete. We here report two cases of SCT with different clinical features.