Mineral rich algae with pine bark improved pain, physical function and analgesic use in mild-knee joint osteoarthritis, compared to Glucosamine: A randomized controlled pilot trial

摘要

Introduction: Osteoarthritis (OA) is characterised by synovial joint pain, functional disability and affects similar to 13 % of people worldwide, of which similar to 16-27 % report Knee-OA (KOA). Glucosamine (Glu) is the most widely used nutraceutical treatment for OA despite a lack of scientific consensus, therefore alternative nutraceutical treatments are required. The aim of this study was to investigate the effect of Lithothamnion species, seawater-derived magnesium and pine bark (Aq(+)) on pain, symptoms and improve physical function in symptomatic (sKOA), compared to Glu.