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首页> 外文期刊>Clinical and experimental ophthalmology >Cyclodialysis cleft repair: A multi‐centred, retrospective case series
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Cyclodialysis cleft repair: A multi‐centred, retrospective case series

机译:CyclodiaLysis裂缝修复:多中心,回顾性盒系列

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摘要

Importance There is a paucity of evidence analysing the treatment of cyclodialysis clefts. Background We describe outcomes following the treatment of this rare condition at six centres internationally. Design Retrospective case series. Participants Thirty‐six patients with a cyclodialysis cleft from 2003 to 2017 were recruited. Methods Clefts were treated with cycloplegic agents, laser therapy and/or surgery. Main Outcome Measures Postoperative best recorded visual acuity (BRVA), intraocular pressure (IOP) and the rate of cleft closure. Results The mean age was 45?±?17?years and 29 (80.6%) patients were male. One eye (2.8%) received only medical therapy, 5 (13.9%) received laser, 14 (38.9%) underwent surgery after laser failure and 16 (44.4%) eyes received exclusively surgery. Over 80% of eyes had a BRVA improvement of more than two lines. Closure was attained in 30 eyes (93.8%; n?=?32), with postoperative stabilized IOP?≥?12?mmHg in 29 eyes (80.6%; n?=?36) and postoperative BRVA ≤20/50 in 20 eyes (58.8%; n?=?34). Improved postoperative BRVA was related to better preoperative BRVA ( P =?0.006) and preoperative IOP?≥?4?mmHg ( P =?0.03). There was no significant difference between treatment approach for IOP?≥?12?mmHg ( P =?0.85) or postoperative BRVA ≤20/50 ( P =?0.80). Only two eyes at last follow‐up required IOP lowering medication. Conclusions and Relevance There was a high closure rate with most eyes eventually requiring surgery. Clinically significant improvements in BRVA were found in most eyes. Improved postoperative BRVA was significantly related to better preoperative BRVA and IOP.
机译:重要性有缺乏证据分析环瘤的治疗。背景技术我们在国际上六个中心治疗这种罕见条件后描述了结果。设计回顾性案例系列。参与者从2003年到2017年患有36名患有的环瘤患者,被招募了2003年至2017年。方法用睫状症药物,激光治疗和/或手术治疗CLEFTS。主要结果术后术后最佳记录的视力(BRVA),眼压(IOP)和裂隙闭合速率。结果平均年龄为45?±17?年龄和29例(80.6%)患者是男性。一只眼睛(2.8%)只接受医疗治疗,5(13.9%)接受激光,14(38.9%)在激光失败后接受手术,并专门接受手术接受了16(44.4%)的眼睛。超过80%的眼睛有两条以上的BRVA改善。 30只眼睛(93.8%; n?= 32)达到闭合,术后稳定的IOP?≥?12?mmhg在29只眼中(80.6%; n?= 36)和术后Brva≤20/ 50英寸(58.8%; n?=?34)。改进的术后BRVA与更好的术前BRVA有关(P = 0.006)和术前IOP?≥?4?mmHg(P = 0.03)。 IOP的治疗方法之间没有显着差异?≥?12?mmHg(p =β0.85)或术后BRVA≤20/ 50(p = 0.80)。最后一次随访中只有两只眼睛需要IOP降低药物。结论和相关性,大多数眼睛最终需要手术。在大多数眼睛中发现了Brva的临床显着改善。改善的术后BRVA与更好的术前BRVA和IOP有显着相关。

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