Background: The long-term management of perianal Crohn's disease for patients on anti-TNF-a therapy remains challenging. Aim: The aim is to evaluate the long-term course and complications of patients with perianal fistulas treated with anti-TNF-a based on their clinical remission and healing on MRI. Methods: Patients were evaluated clinically and by MRI. Deep remission was defined as clinical remission associated with the absence of contrast enhancement and T2 hyperinten-sity on MRI. Flare-free survival, surgery and hospitalizations were compared based on the presence or not of deep remission.
展开▼
