Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity

Naismith O. F.; Griffin C.; Syndikus I; South C.; Mayles H.; Mayles P.; Khoo V; Scrase C.; Graham J.; Hassan S.; Hall E.; Dearnaley D. P.

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Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity

机译：CHHIP试验中的前瞻性和逆计划的强度调节放疗：剂量测定和正常组织毒性的比较

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Aims: The CHHiP (Conventional or Hypofractionated High-dose Intensity Modulated Radiotherapy In Prostate Cancer; CRUK/06/016) trial investigated hypofractionated radiotherapy for localised prostate cancer. Forward- (FP) or inverse-planned (IP) intensity-modulated techniques were permitted. Dose-volume histogram and toxicity data were compared to explore the effects of planning method.

机译：目的：海前癌症（常规或低辐射的高剂量强度调节放疗; CRUK / 06/016）试验研究了局部前列腺癌的次规放射治疗。允许转发 - （FP）或逆计划（IP）强度调制技术。比较剂量直方图和毒性数据，以探讨规划方法的影响。

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来源
《Clinical oncology》 |2019年第9期|共11页
作者
Naismith O. F.; Griffin C.; Syndikus I; South C.; Mayles H.; Mayles P.; Khoo V; Scrase C.; Graham J.; Hassan S.; Hall E.; Dearnaley D. P.;
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作者单位

Royal Marsden NHS Fdn Trust London England;

Inst Canc Res London England;

Clatterbridge Canc Ctr Wirral Merseyside England;

Royal Surrey Cty Hosp Guildford Surrey England;

Clatterbridge Canc Ctr Wirral Merseyside England;

Clatterbridge Canc Ctr Wirral Merseyside England;

Royal Marsden NHS Fdn Trust London England;

Ipswich Hosp Ipswich Suffolk England;

Musgrove Pk Hosp Beacon Ctr Taunton Somerset England;

Inst Canc Res London England;

Inst Canc Res London England;

Royal Marsden NHS Fdn Trust London England;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
DVH; forward planning; intensity-modulated radiotherapy; inverse planning; prostate cancer; toxicity;

机译：DVH;正向规划;强度调制放疗;逆计划;前列腺癌;毒性;

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专利

1. Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity [J] . Naismith O. F., Griffin C., Syndikus I, Clinical oncology . 2019,第9期

机译：CHHIP试验中的前瞻性和逆计划的强度调节放疗：剂量测定和正常组织毒性的比较
2. Multivariable normal-tissue complication modeling of acute esophageal toxicity in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-)radiotherapy [J] . Wijsman Robin, Dankers Frank, Troost Esther G. C., Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2015,第1期

机译：强度调制（化学）放疗治疗的晚期非小细胞肺癌患者急性食管毒性的多变量正常组织并发症建模
3. Long-term Outcomes of a Dose-reduction Trial to Decrease Late Gastrointestinal Toxicity in Patients with Prostate Cancer Receiving Soft Tissue-matched Image-guided Intensity-modulated Radiotherapy [J] . Sasaki Naomi, Yamazaki Hideya, Shimizu Daisuke, Anticancer Research: International Journal of Cancer Research and Treatment . 2018,第1期

机译：剂量减少试验的长期结果，以降低前列腺癌患者的晚期胃肠道毒性接受软组织匹配的图像引导强度调制放射治疗
4. The Combination of Clinical, Dose-Related and Imaging Features Helps Predict Radiation-Induced Normal-Tissue Toxicity in Lung-cancer Patients -- An in-silico Trial Using Machine Learning Techniques [C] . Nalbantov G., Dekker A., De Ruysscher D., Machine Learning and Applications and Workshops (ICMLA), 2011 10th International Conference on . 2011

机译：临床，剂量相关和影像学特征的结合可帮助预测肺癌患者放射诱发的正常组织毒性-使用机器学习技术的计算机模拟试验
5. Volume effects of late term normal tissue toxicity in prostate cancer radiotherapy. [D] . Bonta, Dacian Viorel. 2003

机译：前列腺癌放疗中晚期正常组织毒性的体积效应。
6. Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity [O] . O.F. Naismith, C. Griffin, I. Syndikus, -1

机译：CHHiP试验中的正向和反向计划强度调制放射疗法：剂量测定法和正常组织毒性的比较
7. Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity [O] . O.F. Naismith, C. Griffin, I. Syndikus, 2019

机译：CHHIP试验中的前瞻性和逆计划的强度调节放疗：剂量测定和正常组织毒性的比较

Forward- and Inverse-Planned Intensity-Modulated Radiotherapy in the CHHiP Trial: A Comparison of Dosimetry and Normal Tissue Toxicity

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