MODEL-BASED MABEL APPROACH TO INFORM FIRST-IN-HUMAN DOSE SELECTION OF THE IMMUNO-ONCOLOGY AGONISTIC ANTI-GITR ANTIBODY GWN323.

Ji Y.; Ji T.; Knee D.; He H.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >MODEL-BASED MABEL APPROACH TO INFORM FIRST-IN-HUMAN DOSE SELECTION OF THE IMMUNO-ONCOLOGY AGONISTIC ANTI-GITR ANTIBODY GWN323.

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MODEL-BASED MABEL APPROACH TO INFORM FIRST-IN-HUMAN DOSE SELECTION OF THE IMMUNO-ONCOLOGY AGONISTIC ANTI-GITR ANTIBODY GWN323.

机译：基于模型的MABEL方法，以通知急性肿瘤抗GITR抗体GWN323的第一人体剂量选择。

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来源
《Clinical Pharmacology and Therapeutics》 |2020年第s1期|共2页
作者
Ji Y.; Ji T.; Knee D.; He H.;
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作者单位

Novartis E Hanover NJ USA;

Incyte Wilmington DE USA;

Novartis San Diego CA USA;

Novartis E Hanover NJ USA;

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正文语种 eng
中图分类药理学;
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1. MODEL-BASED MABEL APPROACH TO INFORM FIRST-IN-HUMAN DOSE SELECTION OF THE IMMUNO-ONCOLOGY AGONISTIC ANTI-GITR ANTIBODY GWN323. [J] . Ji Y., Ji T., Knee D., Clinical Pharmacology and Therapeutics . 2020,第S1期

机译：基于模型的MABEL方法，以通知急性肿瘤抗GITR抗体GWN323的第一人体剂量选择。
2. An integrated pharmacology approach for preclinical development of agonistic anti-GITR antibody MK-4166: Application of a mechanistic PK/PD model for implementation of a safe first-in-human (FIH) dosing strategy [J] . Tabrizifard M. European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：临床前开发激动性抗GITR抗体MK-4166的综合药理学方法：机械PK / PD模型在实施安全的人体内（FIH）给药策略中的应用
3. An integrated pharmacology approach for preclinical development of agonistic anti-GITR antibody MK-4166: Application of a mechanistic PK/PD model for implementation of a safe first-in-human (FIH) dosing strategy [J] . Tabrizifard M. European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：激动抗GITR抗体MK-4166临床前发育的综合药理方法：机械PK / PD模型应用安全第一载母增液（FIH）给药策略的应用
4. A Fuzzy Logic Based Approach for Model-Based Regression Test Selection [C] . Mohammed Al-Refai, Walter Cazzola, Sudipto Ghosh ACM/IEEE International Conference on Model Driven Engineering Languages and Systems . 2017

机译：基于模糊逻辑的模型回归测试选择方法
5. First in human dose calculation of a single-chain bispecific antibody targeting glioma using the MABEL approach [O] . Teilo H Schaller, David J Snyder, Ivan Spasojevic, 2020

机译：首先使用MABEL方法计算靶向胶质瘤的单链双特异性抗体的人剂量
6. Anti-GITR Agonistic Monoclonal Antibody INCAGN01876 [O] . 2020

机译：抗GITR激动单克隆抗体INCAMN01876

MODEL-BASED MABEL APPROACH TO INFORM FIRST-IN-HUMAN DOSE SELECTION OF THE IMMUNO-ONCOLOGY AGONISTIC ANTI-GITR ANTIBODY GWN323.

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