DEVELOPMENT OF A PHARMACOKINETIC/ PHARMACODYNAMIC MODEL OF ALN-GO1, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR PRIMARY HYPEROXALURIA.

Attarwala H.; Goel V.; McGregor T.; Erbe D.; Haslett P.; Robbie G.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >DEVELOPMENT OF A PHARMACOKINETIC/ PHARMACODYNAMIC MODEL OF ALN-GO1, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR PRIMARY HYPEROXALURIA.

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DEVELOPMENT OF A PHARMACOKINETIC/ PHARMACODYNAMIC MODEL OF ALN-GO1, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR PRIMARY HYPEROXALURIA.

机译：Aln-Go1药代动力学/药效学模型的研制，对原发性高血脂尿的研究RNAi治疗。

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来源
《Clinical Pharmacology and Therapeutics》 |2018年第1期|共1页
作者
Attarwala H.; Goel V.; McGregor T.; Erbe D.; Haslett P.; Robbie G.;
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作者单位

Alnylam Pharmaceut Cambridge MA USA;

Alnylam Pharmaceut Cambridge MA USA;

Alnylam Pharmaceut Cambridge MA USA;

Alnylam Pharmaceut Cambridge MA USA;

Alnylam Pharmaceut Cambridge MA USA;

Alnylam Pharmaceut Cambridge MA USA;

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正文语种 eng
中图分类药理学;
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1. DEVELOPMENT OF A PHARMACOKINETIC/ PHARMACODYNAMIC MODEL OF ALN-GO1, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR PRIMARY HYPEROXALURIA. [J] . Attarwala H., Goel V., McGregor T., Clinical Pharmacology and Therapeutics . 2018,第Suppla1期

机译：Aln-Go1药代动力学/药效学模型的研制，对原发性高血脂尿的研究RNAi治疗。
2. DEVELOPMENT OF A PHARMACOKINETIC-PHARMACODYNAMIC MODEL OF ALN-TTRSC02, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR THE TREATMENT OF HEREDITARY TTR AMYLOIDOSIS. [J] . Attarwala H., Goel V., Vest J., Clinical Pharmacology and Therapeutics . 2018,第Suppla1期

机译：ALN-TTRSC02药代动力学药物动力学模型的研制，一种治疗遗传性TTR淀粉样术治疗的研究RNAi治疗。
3. DEVELOPMENT OF A PHARMACOKINETIC-PHARMACODYNAMIC MODEL OF ALN-TTRSC02, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR THE TREATMENT OF HEREDITARY TTR AMYLOIDOSIS. [J] . Attarwala H., Goel V., Vest J., Clinical Pharmacology and Therapeutics . 2018,第Suppla1期

机译：ALN-TTRSC02药代动力学药物动力学模型的研制，一种治疗遗传性TTR淀粉样术治疗的研究RNAi治疗。
4. PHARMACOKINETIC AND PHARMACODYNAMIC MODELS FOR THE STUDY OF DRUGS OF ABUSE AND THERAPEUTIC MEDICATIONS IN THE EQUINE RACING INDUSTRY [C] . . 2005

机译：马术竞赛中药物滥用和治疗药物的药代动力学和药代动力学模型
5. Contextualizing the Pharmacokinetics and Pharmacodynamics of Therapeutic Antibodies Through Molecular Imaging and Mathematical Modeling [D] . Tang, Yu. 2021

机译：通过分子成像和数学建模来抑制治疗性抗体的药代动力学和药效学
6. Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia Gravis [O] . Linda L. Kusner, Kristina Yucius, Manjistha Sengupta, 2019

机译：靶向C5的研究性RNAi治疗在重症肌无力的临床前模型中有效
7. A PHASE 2, MULTI-CENTER, OPEN-LABEL TRIAL TO EVALUATE THE SAFETY, PHARMACOKINETICS, PHARMACODYNAMICS AND EXPLORATORY CLINICAL ACTIVITY OF ALN-TTRSC, AN RNAI THERAPEUTIC FOR THE TREATMENT OF PATIENTS WITH TRANSTHYRETIN CARDIAC AMYLOIDOSIS [O] . Gillmore Julian David, Falk Rodney, Maurer Mathew, 2015

机译：第2阶段，多中心，开放式试验，用于评估ALN-TTRSC（一种用于治疗促甲状腺素介导的心肌淀粉样变的患者的RNA疗法）的安全性，药代动力学，药动学和探索性临床活性
8. Preclinical Pharmacodynamic and Pharmacokinetic Studies of Investigational New Drugs [R] . Noker, P. E. 2004

机译：研究性新药的临床前药效学和药代动力学研究

DEVELOPMENT OF A PHARMACOKINETIC/ PHARMACODYNAMIC MODEL OF ALN-GO1, AN INVESTIGATIONAL RNAi THERAPEUTIC FOR PRIMARY HYPEROXALURIA.

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