EVALUATION OF THE EFFECT OF CYP3A4 INHIBITORS AND INDUCERS ON INCB050465 USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION.

Li J.; Ji T.; Chen X.; Yeleswaram S.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >EVALUATION OF THE EFFECT OF CYP3A4 INHIBITORS AND INDUCERS ON INCB050465 USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION.

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EVALUATION OF THE EFFECT OF CYP3A4 INHIBITORS AND INDUCERS ON INCB050465 USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION.

机译：基于生理学药代动力学建模和模拟的CYP3A4抑制剂和诱导剂CYP3A4抑制剂和诱导剂的评价。

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来源
《Clinical Pharmacology and Therapeutics》 |2019年第1期|共2页
作者
Li J.; Ji T.; Chen X.; Yeleswaram S.;
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作者单位

Incyte Wilmington DE USA;

Incyte Wilmington DE USA;

Incyte Wilmington DE USA;

Incyte Wilmington DE USA;

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原文格式 PDF
正文语种 eng
中图分类药理学;
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1. EVALUATION OF THE EFFECT OF CYP3A4 INHIBITORS AND INDUCERS ON INCB050465 USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION. [J] . Li J., Ji T., Chen X., Clinical Pharmacology and Therapeutics . 2019,第Suppla1期

机译：基于生理学药代动力学建模和模拟的CYP3A4抑制剂和诱导剂CYP3A4抑制剂和诱导剂的评价。
2. EVALUATION OF THE EFFECT OF GASTRIC PH MODIFYING AGENTS ON ABSORPTION OF ITACITINIB USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION. [J] . Ji T., Barbour A., Chen X., Clinical Pharmacology and Therapeutics . 2019,第Suppla1期

机译：胃pH改性剂对使用生理基于生理学药代动力学建模和模拟的胃酸改性剂对伊西替尼吸收的影响。
3. EVALUATION OF THE EFFECT OF GASTRIC PH MODIFYING AGENTS ON ABSORPTION OF ITACITINIB USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION. [J] . Ji T., Barbour A., Chen X., Clinical Pharmacology and Therapeutics . 2019,第Suppla1期

机译：胃pH改性剂对使用生理基于生理学药代动力学建模和模拟的胃酸改性剂对伊西替尼吸收的影响。
4. IMPACT OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING ON BENCHMARK DOSE CALCULATIONS FOR TCDD-INDUCED NONCANCER ENDPOINTS [C] . Amy H. Kim, Michael C. Kohn, Christopher J. Portier, International symposium on halogenated environmental organic pollutants and persistent organic pollutants and POPs;DIOXIN;DIOXIN 2001;POPs . 2001

机译：基于生理的药代动力学模型对TCDD诱导的癌端的基准剂量计算的影响
5. Physiologically-Based Pharmacokinetic Modelling: Pre-Clinical and Clinical Pharmacokinetic Studies [D] . Rodrigues, Clare Louise. 2008

机译：基于生理的药代动力学模型：临床前和临床药代动力学研究
6. Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models [O] . Michaela Vossen, Michael Sevestre, Christoph Niederalt, 2007

机译：使用个体偶联全身基于生理的药代动力学（WB-PBPK）模型动态模拟咪达唑仑和CYP3A4抑制剂伊曲康唑的相互作用
7. Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models [O] . 2007

机译：使用个体偶联全身基于生理的药代动力学（WB-PBPK）模型动态模拟咪达唑仑和CYP3A4抑制剂伊曲康唑的相互作用
8. Quantitative Evaluation of Dichloroacetic Acid Kinetics in Human -- A Physiologically-Based Pharmacokinetic Modeling Investigation [R] . Li, T., Schultz, I., Keys, D. A., 2008

机译：人体内二氯乙酸动力学的定量评价 - 基于生理学的药代动力学模型研究

EVALUATION OF THE EFFECT OF CYP3A4 INHIBITORS AND INDUCERS ON INCB050465 USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING AND SIMULATION.

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