首页> 外文期刊>Acta gastro-enterologica Belgica >Ventricular tachyarrhythmia after adalimumab therapy in a patient with Crohn's disease
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Ventricular tachyarrhythmia after adalimumab therapy in a patient with Crohn's disease

机译:克罗恩病患者接受阿达木单抗治疗后的室速性心律失常

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摘要

We report a case of a 19-year-old Caucasian male who was admitted to our Department in February 2010 because of the exacerbation of Crohn's Disease (CD) with a presence of an active perianal fistula. He was then qualified for the biological therapy. A routine electrocardiogram (ECG) performed at that time demonstrated a normal sinus rhythm - 75 beats/min. Subsequently, adalimumab was introduced in standard doses.After two more weeks, the patient returned to our Department to receive the third dose of adalimumab. At the time of admission the patient was asymptomatic, he was in clinical remission. However, auscultation revealed an irregularity of the cardiac rhythm. A 12-lead ECG revealed numerous premature ventricular contractions (PVC's) such as bigeminy and occasionally trigeminy.
机译:我们报告了一例19岁的白人男性,该病例由于患有活动性肛周瘘管的克罗恩病(CD)恶化而于2010年2月入院。然后他有资格进行生物治疗。那时执行的常规心电图(ECG)表现出正常的窦性心律-75次/分钟。随后,以标准剂量引入阿达木单抗。再过两周后,患者返回我科接受第三剂阿达木单抗。入院时患者无症状,正在临床缓解期。然而,听诊发现心律不规则。一个12导联的ECG揭示了许多早发性心室收缩(PVC),例如双排位和偶尔的三叉神经。

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