首页> 外文期刊>Chirality: The pharmacological, biological, and chemical consequences of molecular asymmetry >Absolute configuration of the ocimene monoterpenoids from Artemisia absinthium Artemisia absinthiumArtemisia absinthium
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Absolute configuration of the ocimene monoterpenoids from Artemisia absinthium Artemisia absinthiumArtemisia absinthium

机译:来自 artemisia的绝对构型来自 artemisia absinthium artemisia absinthium artemisia absinthium

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Abstract > The absolute configuration (AC) of the naturally occurring ocimenes (?)‐(3 <fi>S</fi> ,5 <fi>Z</fi> )‐2,6‐dimethyl‐2,3‐epoxyocta‐5,7‐diene ( 1 ) and (?)‐(3 <fi>S</fi> ,5 <fi>Z</fi> )‐2,6‐dimethylocta‐5,7‐dien‐2,3‐diol ( 2 ), isolated from the essential oils of domesticated specimens of <fc> <fi>Artemisia absinthium</fi> </fc> , followed by vibrational circular dichroism (VCD) studies of 1 , as well as from the acetonide 3 and the monoacetate 4 , both derived from 2 , since secondary alcohols are not the best functional groups to be present during VCD studies in solution due to intermolecular associations. The AC follows from comparison of experimental and calculated VCD spectra that were obtained by Density Functional Theory computation at the B3LYP/DGDZVP level of theory. Careful nuclear magnetic resonance (NMR) measurements were compared with literature values, providing for the first time systematic 1 H and 13 C chemical shift data. Regarding homonuclear 1 H coupling constants, after performing a few irradiation experiments that showed the presence of several small long‐range interactions, the complete set of coupling constants for 3 , which is representative of the four studied molecules, was determined by iterations using the PERCH software. This procedure even allowed assigning the <fi>pro</fi> ‐ <fi>R</fi> and <fi>pro</fi> ‐ <fi>S</fi> methyl group signals of the two <fi>gem</fi> ‐dimethyl groups presen </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract Type =“main”> <标题类型=“main”>抽象</ title> >自然发生的印楝(a)的绝对配置(ac) - (3 <fi> s </ fi>, 5 <fi> z </ fi>)-2,6-二甲基-2,3-环氧氢邻-5,7-二烯( 1 </ b>)和(α) - (3 <fi> s < / fi>,5 <fi> z </ fi>)-2,6-二甲基-5,7-dien-2,3-二醇( 2 </ b>),与驯化的精油分离<fc> <fi> artemisia absinthium </ fi> </ fc>,其次是振动圆形二中间(Vcd)研究 1 </ b>,以及乙酰胺 3 </ B>和单乙酸酯 4 / b>,衍生自 2 / b>,因为仲醇不是由于分子间缔组的溶液中的VCD研究期间存在的最佳官能团。通过在B3LYP / DGDZVP理论水平的密度泛函理论计算获得的实验和计算的VCD光谱的比较中遵循。将仔细的核磁共振(NMR)测量与文献值进行比较,提供第一次系统的 1 </ sup> h和 13 </ sup> c化学换档数据。关于同性核 1 </ sup> h偶联常数,在执行少数照射实验后,该辐射实验显示出几个小的远程相互作用,为 3 </ b>的完整耦合常数集合通过使用PERCH软件的迭代来确定四所研究的分子的代表。此过程甚至允许分配<fi> pro </ fi> - <fi> r </ fi> - <fi> pro </ fi> - <fi> s </ fi>甲基群信号的两个<fi> GEM </ FI> - 二甲基抛售 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-16290/'>《Chirality: The pharmacological, biological, and chemical consequences of molecular asymmetry》</a> <b style="margin: 0 2px;">|</b><span>2017年第11期</span><b style="margin: 0 2px;">|</b><span>共10页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Julio Luis F.&option=202" target="_blank" rel="nofollow">Julio Luis F.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Burgue?o‐Tapia Eleuterio&option=202" target="_blank" rel="nofollow">Burgue?o‐Tapia Eleuterio;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Díaz Carmen E.&option=202" target="_blank" rel="nofollow">Díaz Carmen E.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Pérez‐Hernández Nury&option=202" target="_blank" rel="nofollow">Pérez‐Hernández Nury;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=González‐Coloma Azucena&option=202" target="_blank" rel="nofollow">González‐Coloma Azucena;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Joseph‐Nathan Pedro&option=202" target="_blank" rel="nofollow">Joseph‐Nathan Pedro;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Instituto de Ciencias Agrarias Consejo Superior de Investigaciones CientíficasMadrid Spain;</p> <p>Departamento de Química Orgánica Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalMexico City Mexico;</p> <p>Instituto de Productos Naturales y Agrobiología Consejo Superior de Investigaciones CientíficasLa Laguna Tenerife Spain;</p> <p>Escuela Nacional de Medicina y HomeopatíaInstituto Politécnico NacionalMexico City Mexico;</p> <p>Instituto de Ciencias Agrarias Consejo Superior de Investigaciones CientíficasMadrid Spain;</p> <p>Departamento de QuímicaCentro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalMexico City Mexico;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/4812.html" title="结构化学">结构化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=absolute configuration&option=203" rel="nofollow">absolute configuration;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=monoterpenes&option=203" rel="nofollow">monoterpenes;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=ocimenes&option=203" rel="nofollow">ocimenes;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=very‐high‐resolution nuclear magnetic resonance&option=203" rel="nofollow">very‐high‐resolution nuclear magnetic resonance;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=vibrational circular dichroism&option=203" rel="nofollow">vibrational circular dichroism;</a> </p> <div class="translation"> 机译:绝对配置;单点;印象;非常高分辨率的核磁共振;振动圆形二分; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_traditional-medical-research-english_thesis/0201280713605.html">Gastrointestinal effects of Artemisia absinthium Linn. based on traditional Persian medicine and new studies</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hamide Khorram Pazhouh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Hamide Khorram Pazhouh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shokouhsadat Hamedi&option=202" 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和<fi> p </ fi> p - <fc> <fi> n </ fi> <fi> <fi > n </ fi> n,<fc> <fi> n <fi> </ fi> <fc> gfp </ fc> GFP发色团的N-dimethylamino类似物</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704022113526.html">Circularly polarized luminescence of <fc >S</fc>S m (III) and <fc >E</fc>E u (III) complexes with chiral ligand ( <fc > <fi>R</fi> </fc> <fi >R</fi>R / <fc > <fi>S</fi> </fc> <fi >S</fi>S )‐ <fc >BINAPO</fc>BINAPO</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Cotter Daniel&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Cotter Daniel,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Dodder Spencer&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Dodder Spencer,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Klimkowski Valentine J.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Klimkowski Valentine J.,</a> <a href="/journal-foreign-16290/" target="_blank" rel="nofollow" class="tuijian_authcolor">Chirality: The pharmacological, biological, and chemical consequences of molecular asymmetry .</a> <span>2019</span><span>,第4期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:用手性配体(<Fc> <Fi> R <FI> </ FC> </ FI> </ FC> <FC> S </ FC> S m(III)和<FC> E </ FC> E U(III)复合物的圆偏振发光。 > <fi> R </ fi> R / <FC> <FI> S </ FI> <FI> S </ FI> S) - <FC> BINAPO </ FC> BINAPO</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-286211_thesis/0705017952904.html">Extraction of Some Compounds from the Wormwood (Artemisia Absinthium) Plant in Iraq by Organic Methods</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Amjed Abbawe Salih&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Amjed Abbawe Salih,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Dhamer Ismael Madab&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Dhamer Ismael Madab,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ibrahim Awad Mohammed&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ibrahim Awad Mohammed </a> <a href="/conference-foreign-286211/" target="_blank" rel="nofollow" class="tuijian_authcolor">International Conference on Materials Engineering and Science .</a> <span>2020</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:用有机方法提取来自伊拉克伊拉克的蒿木(Astemisia Absinthium)植物的一些化合物</span> </p> </li> <li> <div> <b>8. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/0206198161.html">Molecular phylogenetic and biogeographic study of the genus Artemisia (Asteraceae), with an emphasis on section Absinthium.</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Riggins, Chance.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Riggins, Chance. </a> <span>2008</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:蒿属(菊科)的分子系统发育和生物地理研究,重点是苦艾属部分。</span> </p> </li> <li> <div> <b>9. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040003352608.html">Chemical characterization by GC-MS and in vitro activity against Candida albicans of volatile fractions prepared from Artemisia dracunculus Artemisia abrotanum Artemisia absinthium and Artemisia vulgaris</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Diana Obistioiu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Diana Obistioiu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Romeo T Cristina&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Romeo T Cristina,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ivo Schmerold&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ivo Schmerold,</a> <span>2014</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:GC-MS的化学表征和针对白色念珠菌的挥发性活性成分的体外活性该馏分由青蒿白蒿青蒿和寻常蒿制备</span> </p> </li> <li> <div> <b>10. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000129823607.html">Artemisia absinthium L.: Aplicabilidade na saúde humana / Artemisia absinthium L.: Applicability in human health</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Cleidiane Vedoy Ferraz&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Cleidiane Vedoy Ferraz,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Juciéli Chiamulera das Chagas&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Juciéli Chiamulera das Chagas,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Elisangela Bini Dorigon&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Elisangela Bini Dorigon </a> <span>2020</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:艾蒿的艾蒿50.:aplicabilidade nasaúdeumana/ artemisia蠕虫50.:健康健康的适用性</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_traditional-medical-research-tmr_thesis/0201281932289.html">Gastrointestinal effects of Artemisia absinthium Linn. based on traditional Persian medicine and new studies</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hamide Khorram Pazhouh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . Hamide Khorram Pazhouh</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shokouhsadat Hamedi&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Shokouhsadat Hamedi</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Seyyed Musa-al-Reza Hosseini&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Seyyed Musa-al-Reza Hosseini</a> <span> <a href="/journal-cn-53903/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 传统医学研究(TMR) </a> </span> <span> . 2020</span><span>,第006期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201294239647.html">Creation of Virtual Wi-Fi Access Point and Secured Wi-Fi Pairing, through NFC</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Oussama Stiti&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . Oussama Stiti</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Othmen Braham&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Othmen Braham</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Guy Pujolle&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Guy Pujolle</a> <span> <a href="/journal-cn-56342/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 通讯、网络与系统学国际期刊(英文) </a> </span> <span> . 2014</span><span>,第6期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-13721_thesis/02022967874.html">6×25Fi+FC钢丝绳用钢丝直径比的计算</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=曹玉德&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 曹玉德</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=武岳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,武岳</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=董翠兰&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,董翠兰</a> <span> <a href="/conference-cn-13721/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 全国金属制品信息网第22届年会 </a> <span> <span> . 2010</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020314523736.html">FI--gr--内射模与FI--gr--平坦模</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘天莉莲&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘天莉莲</a> <span> . 2019</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061203498063.html">Wi-Fi网络连接方法、Wi-Fi控制器及Wi-Fi设备</a> <b>[P]</b> . <span> 中国专利: CN104412664B </span> <span> . 2019.10.18</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120108118207.html">Wi-Fi连接方法、终端、Wi-Fi设备、Wi-Fi连接控制方法和服务器</a> <b>[P]</b> . <span> 中国专利: CN105635097A </span> <span> . 2016-06-01</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130417547681.html">Extraction procedure derived monoterpenoid plant Artemisia absinthium l.</a> <b>[P]</b> . <span> 外国专利: <!-- --> ES2405210B1 </span> <span> . 2014-04-02</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:提取方法得自单萜类植物苦艾蒿l。 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130420170700.html">Extraction procedure derived monoterpenoid plant Artemisia absinthium l.</a> <b>[P]</b> . <span> 外国专利: <!-- --> ES2378809B1 </span> <span> . 2013-02-27</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:提取方法得自单萜类植物苦艾蒿l。 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130420154572.html">Extraction procedure derived monoterpenoid plant Artemisia absinthium l.</a> <b>[P]</b> . <span> 外国专利: <!-- --> ES2405210A1 </span> <span> . 2013-05-30</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:提取方法得自单萜类植物苦艾蒿l。 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" 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