Mechanistic Study of the Palladium-Catalyzed Stereoselective Cross-Coupling Reaction of 1,1-Dibromo-3,3,3-trifluoro-2-tosyloxypropene

摘要

We prepared a Pd complex by the oxidative addition of 1,1-dibromo-3,3,3-trifluoro-2-tosyloxypropene to [Pd-(PPh3)(4)]. The atomic distance between Pd and F in the complex was 2.95 angstrom. which was shorter than the sum of the van der Waals radii, suggesting that Pd F interaction played an important role in determining the stereochemical outcome of the Pd-catalyzed cross-coupling reaction of the propene.