Effect of goal-directed crystalloid- versus colloid-based fluid strategy on tissue oxygen tension: a randomised controlled trial

摘要

Background: Sufficient tissue oxygen tension may reduce the risk of postoperative wound infections. Supplemental administration of crystalloids increases subcutaneous oxygen tension (PsqO2). Colloids remain longer in the intravascular system and might therefore increase PsqO2 even more than crystalloids. Therefore, we tested the hypothesis that goal-directed colloid administration increases the perioperative PsqO2 more compared with crystalloid administration.