Second primary malignancies in retinoblastoma patients treated with intra-arterial chemotherapy: the first 10 years

摘要

Background/Aims Survivors of retinoblastoma carry a lifetime risk of secondary malignancies. It is well established that external beam radiation increases this risk; however, the risk with ophthalmic artery chemosurgery (OAC) remains unknown. We report on 10 years of experience with OAC and the rate of second primary malignancy (SPM) development.