Quantitative in vivo assessment of bone microarchitecture in the human knee using HR-pQCT

摘要

Objective: High-resolution peripheral quantitative computed tomography (HR-pQCT)is a novel imaging modality capable of visualizing bone microarchitecture in vivo at human peripheral sites such as the distal radius and distal tibia. This research has extended the technology to provide a non-invasive assessment of bone microarchitecture at the human knee by establishing new hardware, imaging protocols and data analysis.