Evaluation of peri-implant tissues around nanopore surface implants with or without platelet rich fibrin: a clinico-radiographic study

摘要

Objective: To comparatively evaluate peri-implant tissue changes around the nano-pore implant surface with or without platelet rich fibrin (PRF). Material andmethods: For the present study, a total of 17 patientswas initially enrolled (6 females, 11males), and 38 sites (19 control and 19 experimental sites) were randomly assigned to either group 1 (control), i.e. extraction site received immediate implantswithout any PRF, and group 2 (experimental), i.e. extraction sites received immediate implantswith PRF. Clinical and radiographic parameters were recorded for 9 months after the implant-loading phase. Results: Clinically, there was a significant (p<0.001) increase in the peri-implant probing depth fromtheprosthetic phase up to9months in both the groups, and the increase was greater in the control group. However, themean difference in the changes between the two groupswas non-significant. The modified gingiva index for group 2was significantly lower than that for group 1 in the prosthetic phase. Radiographically, in the control group and experimental group, there was a significant increase (<0.01) in bone loss (BL) in themesial and distal aspect of the implant fromthe surgical to prosthetic phase, surgical up to 9months and fromthe prosthetic phase up to 9months. There was greater BL in the control group than in the experimental group in both themesial and distal aspect of the implant; however the difference in BL was non-significant (<0.01). There was greater BL in the distal aspect than in the mesial aspect in both groups; however,the difference in BL was non-significant. Conclusion: PRF treatment may provide away to prevent BL during the surgical-to-prosthetic phase. These resultswere based on a short-term, lowsample randomized clinical study, therefore a long-termstudy with more sites and homogenous sampling is recommended.