Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation

Kabir Ayesha; Jash Chandrima; Payghan Pavan V.; Ghoshal Nanda; Kumar Gopinatha Suresh

首页> 外文期刊>Biochimica et Biophysica Acta. General Subjects >Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation

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Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation

机译：多胺及其类似物调节溶菌酶中的淀粉样蛋白纤维化：对比调查

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Background: Polyamines can induce protein aggregation that can be related to the physiology of the cellular function. Polyamines have been implicated in protein aggregation which may lead to neuropathic and non neuropathic amyloidosis.

机译：背景：多胺可以诱导蛋白质聚集，其可以与细胞功能的生理学有关。多胺在蛋白质聚集中涉及，这可能导致神经性和非神经病淀粉样蛋白症状。

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来源
《Biochimica et Biophysica Acta. General Subjects》 |2020年第5期|共14页
作者
Kabir Ayesha; Jash Chandrima; Payghan Pavan V.; Ghoshal Nanda; Kumar Gopinatha Suresh;
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作者单位

CSIR Indian Inst Chem Biol Organ &

Med Chem Div 4 Raja SC Mullick Rd Kolkata 700032 India;

CSIR Indian Inst Chem Biol Organ &

Med Chem Div 4 Raja SC Mullick Rd Kolkata 700032 India;

CSIR Indian Inst Chem Biol Struct Biol &

Bioinformat Div 4 Raja SC Mullick Rd Kolkata 700032;

CSIR Indian Inst Chem Biol Struct Biol &

Bioinformat Div 4 Raja SC Mullick Rd Kolkata 700032;

CSIR Indian Inst Chem Biol Organ &

Med Chem Div 4 Raja SC Mullick Rd Kolkata 700032 India;

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原文格式 PDF
正文语种 eng
中图分类生物化学;
关键词
Lysozyme; Protein aggregation; Neurodegenerative diseases; Amyloidosis; Polyamine; 1-napthyl acetyl spermine (NASPM); Atomic force microscopy;

机译：溶菌酶;蛋白质聚集;神经变性疾病;淀粉样症;多胺;1-萘基乙酰纤维（NASPM）;原子力显微镜;

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专利

1. Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation [J] . Kabir Ayesha, Jash Chandrima, Payghan Pavan V., Biochimica et Biophysica Acta. General Subjects . 2020,第5期

机译：多胺及其类似物调节溶菌酶中的淀粉样蛋白纤维化：对比调查
2. In vitro investigation of the effect of mesalazine on amyloid fibril formation of hen egg-white lysozyme and defibrillation lysozyme fibrils [J] . European Journal of Pharmacology: An International Journal . 2020,第期

机译：体外调查中甲嘧啶对母蛋白纤维形成母蛋白溶菌酶和除颤溶菌酶原纤维的影响
3. Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity [J] . Kyoungdo Kim, Kwang-su Park, Mi Kyoung Kim, Organic & biomolecular chemistry . 2015,第37期

机译：双氰基乙烯基取代的J147类似物抑制β-淀粉样肽的低聚和原纤化，并保护神经元细胞免受β-淀粉样蛋白诱导的细胞毒性作用
4. Destructive Activity Analysis of Ferritin Derivatives on Lysozyme Amyloid Fibrils [C] . Jan Gombos, Lucia Balejcikova, Marianna Batkova, International Conference on Measurement . 2021

机译：铁蛋白衍生物对溶菌酶淀粉样蛋白原纤维的破坏性活性分析
5. Targeting Polyamine Metabolism in Prostate Cancer: Determining the Role of Reactive Oxygen Species in the Response to Treatment with a Novel Combination of the Polyamine Analogue, BENSpm, and the MTAP Inhibitor, MTDIA [D] . Pellerite, Anthony Jonathan 2018

机译：在前列腺癌中靶向多胺代谢：确定活性氧在多胺类似物BENSpm和MTAP抑制剂MTDIA的新型组合治疗反应中的作用
6. Inhibition of Lysozyme Amyloid Fibrillation by SilybinDiastereoisomers: The Effects of Stereochemistry [O] . Xuanyu Chen, ∥, Xiaomin Deng, 2021

机译：抑制甲硅柳蛋白溶菌酶淀粉样蛋白颤动的抑制作用非对映异构体：立体化学的影响
7. Cellular Polyamines Promote Amyloid-Beta Peptide Fibrillation and Modulate the Aggregation Pathways [O] . Luo Jinghui, Yu Chien-Hung, Yu Huixin, 2013

机译：细胞多胺促进淀粉样蛋白-β肽原纤化并调节聚集途径。

Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation

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