Scandium triflate-catalyzed selective ring opening and rearrangement reaction of spiro-epoxyoxindole and carbonyl compounds

摘要

Scandium triflate-catalyzed reactions between spiro-epoxyoxindole and carbonyl compounds have been disclosed. The reaction with ketones can be used to synthesize spiro[[1,3]dioxolane-4,3'-indolin] species. Furthermore, an unprecedented rearrangement takes place to yield alkylidene oxindole when aromatic aldehydes are used as carbonyl components.