Effect of UVA/Riboflavin Collagen Crosslinking on Biomechanics of Artificially Swollen Corneas

Hatami-Marbini Hamed; Jayaram Sandeep M.

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Effect of UVA/Riboflavin Collagen Crosslinking on Biomechanics of Artificially Swollen Corneas

机译：UVA / Riboflavin Collagen交联对人工肿胀角膜生物力学的影响

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PURPOSE. The purpose of this study was to characterize the relation between corneal hydration and stiffening effects of the UVA/riboflavin collagen crosslinking treatment and to investigate how artificially swelling the cornea prior to this treatment procedure affects tensile property improvement.

机译：目的。本研究的目的是表征UVA /核黄素胶原交联处理的角膜水合和加强效应的关系，并研究在该处理程序之前对角膜的人工溶胀的影响影响了拉伸性质的改善。

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《Investigative ophthalmology & visual science》 |2018年第2期|共7页
作者
Hatami-Marbini Hamed; Jayaram Sandeep M.;
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作者单位

Univ Illinois Mech &

Ind Engn Dept Computat Biomech Res Lab Chicago IL USA;

Univ Illinois Mech &

Ind Engn Dept Computat Biomech Res Lab Chicago IL USA;

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原文格式 PDF
正文语种 eng
中图分类眼科学;
关键词
corneal collagen crosslinking; hydration; hypoosmolar solution; mechanical testing; keratoconus;

机译：角膜胶原交联;水合;低摩尔溶解溶液;机械测试;角蛋白;

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专利

1. Clinical Observation of Transepithelial Corneal Collagen Cross-linking by Iontophoresis of Riboflavin in Treatment of Keratoconus [J] . Na Li, Zhengjun Fan, Xiujun Peng, 眼科学报（英文版） . 2014,第003期
2. Variation in Central Corneal Thickness during Open-or Closed-Eye Riboflavin Instillation for Corneal Collagen Cross-linking [J] . Na Li, Xiujun Peng, Zhengjun Fan, 眼科学报（英文版） . 2013,第004期
3. Impact of crosslinking/riboflavin-UVA-photodynamic inactivation on viability, apoptosis and activation of human keratocytes in vitro [J] . Tanja Stachon, Jiong Wang, Xufei Song, 生物医学研究杂志（英文版） . 2015,第004期
4. Impact of crosslinking/riboflavin-UVA-photodynamic inactivation on viability, apoptosis and activation of human keratocytes in vitro [J] . Tanja Staehon, Jiong Wang, Xufei Song, 生物医学研究杂志：英文版 . 2015,第004期
5. Effect of UVA/Riboflavin Collagen Crosslinking on Biomechanics of Artificially Swollen Corneas [J] . Hatami-Marbini Hamed, Jayaram Sandeep M. Investigative ophthalmology & visual science . 2018,第2期

机译：UVA / Riboflavin Collagen交联对人工肿胀角膜生物力学的影响
6. Collagen Fiber Diameter in the Rabbit Cornea After Collagen Crosslinking by Riboflavin/UVA. [J] . Seiler T Cornea . 2004,第5期

机译：核黄素/ UVA交联胶原后兔角膜中的胶原纤维直径。
7. BAC-EDTA transepithelial riboflavin-UVA crosslinking has greater biomechanical stiffening effect than standard epithelium-off in rabbit corneas [J] . Andre A.M. Torricelli, Matthew R. Ford, Vivek Singh, Experimental Eye Research . 2014,第Null期

机译：在兔角膜中，BAC-EDTA经上皮核黄素-UVA交联具有比标准上皮脱落更大的生物力学增强作用
8. Quantifying the effects of UV-A/riboflavin crosslinking on the elastic anisotropy and hysteresis of the porcine cornea by noncontact optical coherence elastography [C] . Manmohan Singh, Jiasong Li, Raksha Raghunathan, Optical Elastography and Tissue Biomechanics IV . 2017

机译：通过非接触光学相干弹性成像技术定量分析UV-A /核黄素交联对猪角膜弹性各向异性和滞后的影响
9. Bioengineered collagen composite materials as implantable artificial corneas. [D] . Rafat, Mehrdad. 2007

机译：生物工程胶原复合材料，可植入人工角膜。
10. BAC-EDTA transepithelial riboflavin-UVA crosslinking has greater biomechanical stiffening effect than standard epithelium-off in rabbit corneas [O] . Andre A. M. Torricelli, Matthew R. Ford, Vivek Singh, -1

机译：在兔角膜中BAC-EDTA经上皮核黄素-UVA交联比标准上皮脱落具有更大的生物力学增强作用
11. High-intensity corneal collagen crosslinking with riboflavin and UVA in rat cornea. [O] . Yirui Zhu, Peter S Reinach, Hanlei Zhu, 2017

机译：高强度角膜胶原蛋白与大鼠角膜中的核黄素和UVa交联。

Effect of UVA/Riboflavin Collagen Crosslinking on Biomechanics of Artificially Swollen Corneas

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