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Impact of social characteristics on the treatment of patients with ischaemic events and patent foramen ovale

机译:社会特征对缺血性事件和卵圆孔未闭患者治疗的影响

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Objective Percutaneous closure of a patent foramen ovale (PFO) is a technically simple and safe procedure. PFO is a common finding present in up to one third of the population. Although several conditions such as stroke, migraine, and sleep apnoea have been associated with a PFO, as underlined by observational studies, no causal relationship has been documented so far. As this setting may potentially leave more space for the involved physicians for the choice of treatment, we hypothesized that social characteristics of the patient with a PFO might play a role. Methods We retrospectively analysed the data of 153 patients with a cerebrovascular and/or peripheral ischaemic event with the diagnosis of a PFO as documented in echocardiography from 2000 until 2005 at the University Hospital in Zurich, Switzerland. Results Forty-four patients (= 23%) underwent catheter-based PFO closure. There was no significant difference with respect to age (< 40 years: P = 0.094, ns; 40-59 years: P = 0.923, ns; ≥ 60 years: P = 0.234, ns), gender (P = 0.356, ns) and insurance status (< 40 years: P = 0.15, ns; 40-59 years: P = 0.37, ns; ≥ 60 years: P = 0.26, ns) between those who underwent percutaneous PFO closure and those who did not. Conclusion We conclude from this single-centre experience that social characteristics of patients only have a marginal impact on the indication of percutaneous closure of a PFO, if at all.
机译:目的经皮闭合卵圆孔未闭(PFO)是一种技术上简单且安全的手术。 PFO是多达三分之一人口中的常见发现。尽管观察性研究强调,中风,偏头痛和睡眠呼吸暂停等几种疾病与PFO相关,但迄今尚未发现因果关系。由于此设置可能会给相关的医生留下更多选择治疗的空间,因此我们假设PFO患者的社会特征可能会起作用。方法我们回顾性分析了2000年至2005年在瑞士苏黎世大学医院超声心动图记录的153例诊断为PFO的脑血管和/或外周缺血事件的患者的数据。结果44例患者(= 23%)接受了基于导管的PFO封闭术。年龄(<40岁:P = 0.094,ns; 40-59岁:P = 0.923,ns;≥60岁:P = 0.234,ns),性别(P = 0.356,ns)没有显着差异。以及经皮PFO封堵者与未接受封堵者之间的保险状态(<40年:P = 0.15,ns; 40-59年:P = 0.37,ns;≥60年:P = 0.26,ns)。结论我们从这一单一中心的经验得出结论,患者的社会特征仅对PFO经皮闭合的指征有边际影响(如果有的话)。

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