Anxiolytic- and antidepressant-like activities of hydroethanol leaf extract of Newbouldia laevis (P.Beauv.) Seem. (Bignoniaceae) in mice

摘要

Ethnopharmacological relevance: Newbouldia laevis (Bignoniaceae) is a woody tropical plant commonly found in southwest Nigeria. Ethnobotanical survey and literature revealed its application in the management of CNS disorders e.g. psychosis, insomnia, convulsions and associated anxiety and depression. This study evaluated the anxiolytic and antidepressant activities of the hydroethanol leaf extract of N. laevis in mice.