A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma

de Freitas Morel Lucas Junqueira; de Azevedo Bruna Cestari; Carmona Fabio; Contini Silvia Helena Taleb; Teles Aristonio Magalhaes; Ramalho Fernando Silva; Bertoni Bianca Waleria; Franca Suzelei de Castro; Borges Marcos de Carvalho; Pereira Ana Maria Soares

首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma

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A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma

机译：Eclipta Prostrata（L.）L.（菊科）的标准化甲醇提取物降低了支气管高反应性和在哮喘的小鼠模型中的Th2细胞因子的生产

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摘要

Ethnopharmacological relevance: Eclipta prostrata (L.) L. (Asteraceae) has been used in Brazilian traditional medicine to treat asthma and other respiratory illnesses. Aims of the study: To investigate the effects of different doses of a standardized extract of E. prostrata using a murine model of allergen induced asthma.

机译：民族科医药相关性：Eclipta prostrata（L.）L.（菊科）已被用于巴西中药治疗哮喘和其他呼吸疾病。该研究的目的：使用过敏原诱导的哮喘的小鼠模型研究不同剂量的E. prostrata标准化提取物的影响。

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来源
《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs》 |2017年第2017期|共9页
作者
de Freitas Morel Lucas Junqueira; de Azevedo Bruna Cestari; Carmona Fabio; Contini Silvia Helena Taleb; Teles Aristonio Magalhaes; Ramalho Fernando Silva; Bertoni Bianca Waleria; Franca Suzelei de Castro; Borges Marcos de Carvalho; Pereira Ana Maria Soares;
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作者单位

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

Univ Fed Goias Inst Ciencias Biolag Dept Botem Campus Samambaia Esperanga BR-74690900 Goiania;

Univ Seto Paulo Faculdade Med Ribeirao Preto Bandeirantes 3900 BR-14049900 Ribeirao Preto SP;

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

Univ Seto Paulo Faculdade Med Ribeirao Preto Bandeirantes 3900 BR-14049900 Ribeirao Preto SP;

Univ Ribeirao Preto Dept Biotecnol Plantas Medicinais Costabile Romano 2201 BR-140960 Ribeirao;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Eclipta prostrate; Wedelolactone; Demethylwedelolactone; Oroboside; Anti-inflammatory; Asthma;

机译：Eclipta prestrate;Wedelolone;Demethylwedelontone;oroboside;抗炎;哮喘;

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1. A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma [J] . de Freitas Morel Lucas Junqueira, de Azevedo Bruna Cestari, Carmona Fabio, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2017,第期

机译：Eclipta Prostrata（L.）L.（菊科）的标准化甲醇提取物降低了支气管高反应性和在哮喘的小鼠模型中的Th2细胞因子的生产
2. Validated UPLC‐MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract of Eclipta prostrata Eclipta prostrata Eclipta prostrata L. [J] . Du Guangyan, Fu Lingling, Jia Jun, Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2018,第6期

机译：验证的UPLC-MS / MS方法，用于定量大鼠等离子体和组织中的7种化合物：在口服施用Eclipta prostrata Eclipta Prostrata Eclipta Prostrata eClipta prostrata eNlipta prostrata eNlipta prostrata eClipta prostrata提取物中的药代动力学和组织分布研究。
3. A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models [J] . Jun Chen, Linhong Deng, Daniela Dreymüller, Scientific reports. . 2016,第1期

机译：新型肽ADAM8抑制剂可减轻小鼠哮喘模型的支气管高反应性和Th2细胞因子介导的炎症
4. Effects of Over Expression of LTC4 Synthase Gene on Development of Th2 Type Airway Inflammation in Murine Model of Bronchial Asthma [C] . K. Honda, M. Arima, G. Cheng Asia Pacific Congress of Allergology and Clinical Immunology . 2004

机译：LTC4合成酶基因表达对支气管哮喘鼠模型Th2型气道炎症发育的影响
5. Helminthostachys zeylanica Water Extract Ameliorates Airway Hyperresponsiveness and Eosinophil Infiltration by Reducing Oxidative Stress and Th2 Cytokine Production in a Mouse Asthma Model [O] . Wen-Chung Huang, Nai-Chun Ting, Yu-Ling Huang, 2020

机译：通过在小鼠哮喘模型中减少氧化应激和Th2细胞因子产生冬青氏菌唑氏唑类水提取物改善了气道高反应性和嗜酸性粒细胞渗透
6. A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models [O] . Chen, Jun, Deng, Linhong, Müller, Bernd, 2016

机译：新型肽ADAM8抑制剂可减轻小鼠哮喘模型的支气管高反应性和Th2细胞因子介导的炎症

A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma

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